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Yaroustovsky et al. Vessel Plus 2017;1:49-60 Vessel Plus
DOI: 10.20517/2574-1209.2017.11
www.vpjournal.net
Review Open Access

Blood purification in intensive care

patients with multiple organ dysfunction

syndrome and sepsis after cardiac surgery

Michael Yaroustovsky, Marina Abramyan, Ekaterina Komardina, Helen Nazarova

Federal State Budget Institution (Bakulev National Scientific and Practical Centre for Cardiovascular Surgery, Bakulev NSPCCS), the Ministry of
Healthcare of the Russian Federation, 121552 Moscow, Russia.
Correspondence to: Prof. Michael Yaroustovsky, Federal State Budget Institution (Bakulev National Scientific and Practical Centre for Cardiovascular
Surgery, Bakulev NSPCCS), the Ministry of Healthcare of the Russian Federation, Rublevskoe highway, 135, 121552 Moscow, Russia.
E-mail: mbyar@yandex.ru
How to cite this article: Yaroustovsky M, Abramyan M, Komardina E, Nazarova H. Blood purification in intensive care patients with multiple organ
dysfunction syndrome and sepsis after cardiac surgery. Vessel Plus 2017;1:49-60.

Prof. Michael Yaroustovsky, the Chief of the Department of Detoxication and Endoscopy at Bakoulev Scientific
Center for Cardiovascular Surgery, Corresponding Member of RAS, is a well-known Russian scientist who has
made significant contributions to the development of modern technologies of extracorporeal blood purification
in the treatment of critical states. He owns the absolute priority in the development and the introduction into
the clinical practice of Russian clinics of modern methods of correction and maintaining homeostasis, including
albumin dialysis, combined plasma filtration and adsorption, selective hemoperfusion, etc. at extremely severe
contingent of patients of different age groups having multiple organ failure and septic complications after
cardiac surgery. He is the author of more than 270 scientific articles, including 7 monographs and the first
Russian manual on Blood purification in Intensive Care.
ABSTRACT
Article history: Extracorporeal blood purification is becoming increasingly important in intensive therapy
Received: 11-04-2017 for multiple organ dysfunction syndrome (MODS) and sepsis, considering all of their
Accepted: 08-06-2017 pathophysiological aspects. The results of treatment, particularly in children, considering
Published: 27-06-2017 their anatomical and physiological features, are related to the severity and progression of
organ failure, the indications that are found, the choice of method, and the timely initiation
Key words: of blood purification. Multiple organ support therapy is the aim of introducing and applying
Extracorporeal blood purification, blood purification today. Various extracorporeal blood purification techniques directly affect
acute kidney injury, the molecular and electrolyte composition of blood and influence all structures of the human
acute liver failure, body, which can allow us to correct, recover, replace and maintain homeostasis in MODS. The
extracorporeal membrane potential of new extracorporeal molecular technologies allows their successful use in severe
oxygenation, cardiac and respiratory failure, acute kidney injury and hepatic dysfunction and in complex
sepsis, therapy for severe infections and sepsis and extreme metabolic violations. Adult and pediatric
selective lipopolysaccharide- patients after cardiac surgery with cardiopulmonary bypass form a special cohort that often
adsorption, requires the application of various intra- and extracorporeal techniques due to the development
critical condition, of MODS, infections and sepsis in the postoperative period.
cardiovascular surgery

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