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Bilovol et al. Relationship between atrial fibrillation, BMI and adipokines
DECLARATIONS JAMA 2004;292:2471-7.
8. Guglin M, Maradia K, Chen R, Curtis AB. Relation of obesity
to recurrence rate and burden of atrial fibrillation. Am J Cardiol
Authors’ contributions 2011;107:579-82.
Study design: O. Bilovol, I. Ilchenko 9. Frost L, Hune LJ, Vestergaard P. Overweight and obesity as risk
Development of methodology: O. Bilovol factors for atrial fibrillation or flutter: the Danish diet, cancer, and
Collection of data: O. Bilovol, Y. Shaposhnikova, I. health study. Am J Med 2005;118:489-95.
Ilchenko, A. Shalimova 10. Murphy NF, MacIntyre K, Stewart S, Hart CL, Hole D, McMurray JJ.
Analysis and/or interpretation of data: O. Bilovol, Y. Long-term cardiovascular consequences of obesity: 20-year follow-
up of more than 15 000 middle-aged men and women (the Renfrew-
Shaposhnikova, I. Ilchenko, A. Shalimova Paisley study). Eur Heart J 2006;27:96-106.
Writing (not revising) all or sections of the manuscript: 11. Goette A, Staack T, Röcken C, Arndt M, Geller JC, Huth C, Ansorge
O. Bilovol, Y. Shaposhnikova, I. Ilchenko, A. Shalimova S, Klein HU, Lendeckel U. Increased expression of extracellular
Manuscript review: O. Bilovol, I. Ilchenko signal-regulated kinase and angiotensin-converting enzyme in human
Supervision: O. Bilovol atria during atrial fibrillation. J Am Coll Cardiol 2000;35:1669-77.
12. Dzeshka MS, Lip GY, Snezhitskiy V, Shantsila E. Cardiac fibrosis in
Financial support and sponsorship patients with atrial fibrillation: mechanisms and clinical implications.
J Am Coll Cardiol 2015;66:943-59.
None. 13. Nattel S, Harada M. Atrial remodeling and atrial fibrillation:
recent advances and translational perspectives. J Am Coll Cardiol
Conflicts of interest 2014;63:2335-45.
There are no conflicts of interest. 14. Ito K, Date T, Kawai M, Nojiri A, Narui R, Hioki M, Tanigawa S,
Yamashita S, Tokuda M, Inada K, Matsuo S, Yamane T, Yoshimura
Patient consent M. Morphological change of left atrium in obese individuals. Int J
Cardiol 2011;152:117-9.
Each patient was informed the study and gave their 15. Munger TM, Dong YX, Masaki M, Oh JK, Mankad SV, Borlaug BA,
consent. Asirvatham SJ, Shen WK, Lee HC, Bielinski SJ, Hodge DO, Herges
RM, Buescher TL, Wu JH, Ma C, Zhang Y, Chen PS, Packer DL,
Ethics approval Cha YM. Electrophysiological and hemodynamic characteristics
The study protocol was supported by the Ethics associated with obesity in patients with atrial fibrillation. J Am Coll
Committee of the Kharkiv National Medical University. Cardiol 2012;60:851-60.
16. Ouchi N, Parker JL, Lugus JJ, Walsh K. Adipokines in inflammation
and metabolic disease. Nat Rev Immunol 2011;11:85-97.
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