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Bilovol et al.                                                                                                                                     Relationship between atrial fibrillation, BMI and adipokines

           DECLARATIONS                                          JAMA 2004;292:2471-7.
                                                              8.   Guglin  M,  Maradia  K,  Chen  R,  Curtis  AB.  Relation  of  obesity
                                                                 to  recurrence  rate  and  burden  of  atrial  fibrillation.  Am J Cardiol
           Authors’ contributions                                2011;107:579-82.
           Study design: O. Bilovol, I. Ilchenko              9.   Frost  L,  Hune  LJ,  Vestergaard  P.  Overweight  and  obesity  as  risk
           Development of methodology: O. Bilovol                factors  for  atrial  fibrillation  or  flutter:  the  Danish  diet,  cancer,  and
           Collection of  data:  O.  Bilovol,  Y.  Shaposhnikova,  I.   health study. Am J Med 2005;118:489-95.
           Ilchenko, A. Shalimova                             10.  Murphy NF, MacIntyre K, Stewart S, Hart CL, Hole D, McMurray JJ.
           Analysis  and/or  interpretation of  data:  O.  Bilovol,  Y.   Long-term cardiovascular consequences of obesity: 20-year follow-
                                                                 up of more than 15 000 middle-aged men and women (the Renfrew-
           Shaposhnikova, I. Ilchenko, A. Shalimova              Paisley study). Eur Heart J 2006;27:96-106.
           Writing (not revising) all or sections of the manuscript:   11.  Goette A, Staack T, Röcken C, Arndt M, Geller JC, Huth C, Ansorge
           O. Bilovol, Y. Shaposhnikova, I. Ilchenko, A. Shalimova  S,  Klein  HU,  Lendeckel  U.  Increased  expression  of  extracellular
           Manuscript review: O. Bilovol, I. Ilchenko            signal-regulated kinase and angiotensin-converting enzyme in human
           Supervision: O. Bilovol                               atria during atrial fibrillation. J Am Coll Cardiol 2000;35:1669-77.
                                                              12.  Dzeshka MS, Lip GY, Snezhitskiy V, Shantsila E. Cardiac fibrosis in
           Financial support and sponsorship                     patients with atrial fibrillation: mechanisms and clinical implications.
                                                                 J Am Coll Cardiol 2015;66:943-59.
           None.                                              13.  Nattel  S,  Harada  M.  Atrial  remodeling  and  atrial  fibrillation:
                                                                 recent  advances  and translational  perspectives.  J  Am Coll  Cardiol
           Conflicts of interest                                 2014;63:2335-45.
           There are no conflicts of interest.                 14.  Ito K, Date T, Kawai M, Nojiri A, Narui R, Hioki M, Tanigawa S,
                                                                 Yamashita S, Tokuda M, Inada K, Matsuo S, Yamane T, Yoshimura
           Patient consent                                       M. Morphological change of left atrium in obese individuals. Int J
                                                                 Cardiol 2011;152:117-9.
           Each patient was informed the study and gave their   15.  Munger TM, Dong YX, Masaki M, Oh JK, Mankad SV, Borlaug BA,
           consent.                                              Asirvatham SJ, Shen WK, Lee HC, Bielinski SJ, Hodge DO, Herges
                                                                 RM, Buescher TL, Wu JH, Ma C, Zhang Y, Chen PS, Packer DL,
           Ethics approval                                       Cha YM. Electrophysiological  and hemodynamic  characteristics
           The study protocol was supported by the Ethics        associated with obesity in patients with atrial fibrillation. J Am Coll
           Committee of the Kharkiv National Medical University.  Cardiol 2012;60:851-60.
                                                              16.  Ouchi N, Parker JL, Lugus JJ, Walsh K. Adipokines in inflammation
                                                                 and metabolic disease. Nat Rev Immunol 2011;11:85-97.
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