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Rao. Vessel Plus 2022;6:24  https://dx.doi.org/10.20517/2574-1209.2021.91        Page 7 of 23

               Table 2. Normal intra-cardiac velocities by Doppler ultrasound*
                Site                Children m/s; mean (range)          Adults m/s; mean (range)
                Mitral inflow       1.00 (0.8-1.3)                      0.90 (0.6-1.3)
                Tricuspid inflow    0.60 (0.5-0.8)                      0.50 (0.3-0.7)
                Pulmonary artery    0.90 (0.7-1.1)                      0.75 (0.6-0.9)
                Left ventricle      1.00 (0.7-1.2)                      0.90 (0.7-1.1)
                Aorta               1.50 (1.2-1.8)                      1.35 (1.0-1.7)

               *Data abstracted from Refs. [15,16] .























                Figure 7. Two-dimensional echo and color Doppler video frames are presented to demonstrate turbulent flow patterns. (A) Turbulent
                blood flow (arrow) commences at the level of the aortic valve (arrow - TF) because of aortic stenosis while (B) the turbulence begins at
                the ductus (TF) shown by arrow. Aorta (Ao), descending aorta (DAo), left ventricle (LV), and main pulmonary artery (MPA) are
                labeled. Reproduced from Ref. [19] .


               ECHO PROTOCOL
               Echo-Doppler studies are carried out by placing the transducer over multiple echo windows, namely, left
               parasternal area, cardiac apex, subcostal region, and suprasternal area. Data from parasternal long-axis
               [Figure 2], parasternal short-axis [Figure 8], apical four-chamber, apical five-chamber [Figure 9], subcostal
               [Figures 10 and 11], and suprasternal notch [Figures 12 and 13] views are usually documented.

               M-mode and 2D recordings along with PW, CW, color flow Doppler assessment, as deemed suitable, are
               carried out methodically. Examination by Doppler should include (1) search for shunts across the atrial and
               ventricular septae; (2) exclude atrio-ventricular (AV) valve insufficiency by interrogation of the left and
               right atria proximal to the mitral and tricuspid valves, respectively; (3) explore the left/right ventricular
               inflow sites to exclude mitral/tricuspid stenosis; (4) examine the left and right ventricular outflow tracts to
               detect aortic and pulmonary valve insufficiency, respectively; (5) interrogate the pulmonary artery and aorta
               for semilunar valve stenosis; and (6) examination looking for aortic coarctation and patency of the ductus
               arteriosus.  Investigation  of  additional  sites  on  the  basis  of  findings  of  clinical,  laboratory  and
               echocardiographic examination should be performed as well.

               METHODS OF ESTIMATION OF PULMONARY ARTERY PRESSURE
               Frequently, neonatologists, pediatric cardiologists, pediatric intensivists, cardiac surgeons and pediatricians
               request for evaluation of PA pressures in their patients. Although the reasons for such request vary from
               one specialist to the other, the magnitude of the PA pressure is a central component in managing many
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