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Villeda-Hernandez et al. Soft Sci 2024;4:14                               Soft Science
               DOI: 10.20517/ss.2023.52



               Review Article                                                                Open Access



               Soft alchemy: a comprehensive guide to chemical

               reactions for pneumatic soft actuation


               Marcos Villeda-Hernandez 1  , Benjamin C. Baker 1  , Christian Romero 2  , Jonathan M. Rossiter 2  ,
               Charl FJ.  Faul 1,*
               1
                School of Chemistry, University of Bristol, Bristol BS8 1TS, UK.
               2
                School of Engineering Mathematics and Technology, and Bristol Robotics Laboratory, University of Bristol, Bristol BS8 1TW, UK.
               * Correspondence to: Prof. Charl FJ. Faul, School of Chemistry, University of Bristol,  Cantock’s Close, Bristol BS8 1TS, UK. E-mail:
               charl.faul@bristol.ac.uk
               How to cite this article: Villeda-Hernandez M, Baker BC, Romero C, Rossiter JM, Faul CFJ. Soft alchemy: a comprehensive guide
               to chemical reactions for pneumatic soft actuation. Soft Sci 2024;4:14. https://dx.doi.org/10.20517/ss.2023.52
               Received: 15 Nov 2023  First Decision: 27 Dec 2023  Revised: 31 Jan 2024  Accepted: 25 Mar 2024  Published: 29 Mar 2024

               Academic Editors: Zhifeng Ren, Ramsés Valentin Martínez  Copy Editor: Dong-Li Li  Production Editor: Dong-Li Li

               Abstract
               Soft robotics has emerged as a transformative field, leveraging bio-inspired novel actuation mechanisms to enable
               more adaptable, compliant, and sophisticated robotic systems. However, the portability of soft pneumatic
               actuators is typically constrained by the tethering to bulky power sources. This review offers a thorough analysis of
               autonomous power alternatives facilitated by chemical reactions for gas generation and absorption, a concept
               analogous to biological energy conversion processes. These bio-inspired strategies propel soft pneumatic actuators
               towards new horizons of autonomy and portability, essential for real-world applications. This comprehensive
               review explores the critical intersection of gas evolution reactions (GERs) and gas consumption reactions (GCRs)
               as a power source for pneumatic actuation in soft robotics. We here emphasize the importance and impact of bio-
               inspired design, control, efficiency, safety, and sustainability within soft robotics to not only mimic biological
               motions but to enhance them. This review explores the fundamentals of both pneumatic and chemically powered
               actuation, highlighting the need for careful consideration of reaction kinetics. Additionally, this work highlights key
               aspects of smart materials that draw from biological structures and response mechanisms, along with state-of-the-
               art techniques for precise pressure modulation. Finally, we chart prospective development pathways and provide a
               future outlook for bio-inspired soft robotics, emphasizing the transformative impact of integrating chemical
               actuation methods. This exploration underlines the quest for further autonomy in soft robotic systems and points
               towards the future opportunities in this exciting and fast-developing field.

               Keywords: Soft robotics, chemistry, pneumatic actuation, design, chemical power source, oscillating systems,
               chemical reactions, chemically driven pneumatic actuation





                           © The Author(s) 2024. Open Access This article is licensed under a Creative Commons Attribution 4.0
                           International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing,
                           adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as
               long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and
               indicate if changes were made.

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