Page 338 - Read Online

The average age and sex of tissue recipients is depicted DISCUSSION
in Table 5.
Thirty patients underwent a total of 52 transplants; 88.5% The HUEC skin bank collected tissue from 45 cadaveric
of the transplants were performed at the HUEC, 7.7% were donors during its 1st year of operation. Upon a review
performed at the Regional University Hospital of Northern of the Brazilian literature, a number of similar collections
[8]
Paraná in Londrina city, 2% at the Vita Batel Hospital of were noted from another operational skin bank. The
Curitiba and 2% at the São Paulo Regional Hospital in numbers in this study compare favorably with available
[9]
Santa Catarina state [Figure 1]. international data. Of great importance was the ability
of the HUEC skin bank to address the local demand.
A total allograft area of 28,940.83 cm² was transplanted,
with the largest area grafted in a single procedure at The average age of the skin donors was similar to that
[9]
1,816.4 cm² and the smallest at 68 cm². The largest amount of the donors of the Helsinki skin bank but lower
of tissue grafted to a single patient was 7,284.75 cm². than the average age of donors to the Porto Alegre skin
[8]
A single patient could receive skin from up to 10 donors, bank. The higher number of younger donors may be
with an average of 3 donors and a minimum of one donor justified by the higher mortality rates within this cohort
per surgical intervention [Table 6]. in the city of Curitiba due to traffic accidents and physical
assaults, which were 23.2 and 42.1 per 100,000 inhabitants,
Most patients who received allografts were burn victims, respectively, according to the information department of
corresponding to 25 patients and 45 skin transplantation Unified Health System (DATASUS 2008). [10]
procedures. The indications for the other 7 transplants
are shown in Figure 2. An equal number of women and men were donors, despite
the number of deaths from external causes in 2012 being
Among the burn victims, the vast majority (96%) [11]
presented with third‑degree burns. The most extensively 3.36 times higher for males in Curitiba.
compromised body surface area was 75% and the lowest The vast majority of donors in Curitiba were of white‑colored
10%, with an average of 38.64% of the total body surface skin, justified by a predominantly Caucasian population in
area [Table 7]. the region. According to Database of Unified Health System
of Brazilian government (DATASUS) [11] recordson mortality in
The body areas which were transplanted are shown in
Table 8. Curitiba in 2012, 8,218 white skin people died as compared

Table 3: Batches of generated skin Table 5: Recipients profile
Variable Descriptive statistics Variable Descriptive statistics n (%)
Gender
Batch number Percentage
Female 10 (33.33)
Quantity (number of batches) Male 20 (66.67)
Approved for distribution Total 30 (100.00)
Transplanted 38 4.91 Age
Stored in the bank 3 3.70 Average ( ± SD) 29.09 years (22.72)
Discarded 38 46.91 Maximum 85 years
In process quarantine 2 2.47 Minimum 18 days
Total 81 100.00
Reasons for batch discard SD: Standard deviation
Growth of coagulase-negative 16 42.11
staphylococci Table 6: Grafted skin
Growth of bacillus 7 18.42
Gram-positive not Clostridium Variable Descriptive statistics (n)
Growth of filamentous Fungi 6 15.79 Transplanted skin area (in cm )
2
Growth of positive coagulase 4 10.53 Total 28,940.82
Staphylococcus Maximum per surgery 1,816.4
Growth of Enterococcus spp. 3 7.89 Minimum per surgery 68
Positive for syphilis 2 5.26 Maximum per patient 7,284.75
Lung cancer 2 5.26 Minimum per patient 68
Total 40 105.26
Average per surgery 556.55
Average per patient 964.694
Relation between donors × recipients
Table 4: Relation between benefited patients and donors
Maximum of donors per patient 10
n Maximum of donors per surgery 3
Total of benefited patients 30 Minimum of donors per patient 1
Average of benefited patients per donor ( ± SD) 2.36 (1.35) Minimum of donors per surgery 1
Maximum of patients benefited per donor 5 Average of donors per patient 1.93
SD: Standard deviation Average of donors per surgery 1.25

Plast Aesthet Res || Vol 2 || Issue 6 || Nov 12, 2015 329