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Table 3: Patient’s quality of life evaluated with QoL-Q  result. The pre- and postoperative module was comprised
             Thinking about   Preoperatively Postoperatively   P  of 11 multiple-response questions. The questionnaire was
             the body part that   (%)*     (%)*               conceived by the authors as a test of self-administration,
             you turned to the                                only for patients candidate to undergo all type of
             plastic surgeon:                                 cosmetic procedures. Questionnaires were filled out in an
             How do you feel in   8 (27)  27 (90)   0.0001†   anonymous fashion. Preoperative surveys were completed
             your clothes?
             How you feel when   5 (17)   28 (93)   0.0001†   during the initial consultation, and postoperative
             you're in the midst                              surveys were completed at the 6 months postoperative
             of the people?                                   visit. This was a cross-sectional study and therefore the
             How do you feel   1 (3)      29 (97)   0.0001†   patients who filled out preoperative surveys may be
             showing the part of                              different from those who filled out postoperative surveys.
             the body?                                        Because surveys were filled out anonymously, there was
             Do you feel safe in   15 (50)  24 (80)  0.002†   no way to identify those patients who filled out both
             working life?                                    the preoperative and postoperative surveys. Statistical
             Do you feel safe in   11 (37)  26 (87)  0.065    analysis was performed using descriptive and summary
             your private life?
             Do you feel safe of   1 (3)  26 (87)   0.0001†   statistics to identify a central tendency. An unpaired t-test
             the body part for                                was performed to examine the significance of changes in
             which you have                                   mean scores of satisfaction. Fisher’s exact test was used
             addressed to the                                 to detect any significant differences between preoperative
             plastic surgeon                                  and postoperative satisfaction for a dichotomous
             Do you feel safe of   18 (30)  25 (83)  0.068    outcome. A value of P < 0.05 was considered significant.
             your body?
             Do you feel      7 (23)      25 (83)   0.0001†
             reassured?                                       Inclusion criteria were: (1) patients from 18 to 40 years old
             Do you think your   13 (43)  24 (80)   0.003†    in good health; and (2) patients with chronical acne scars
             quality of life is                               on the cheeks.
             good?
             Do you think to be   12 (40)  22 (73)  0.004†    Exclusion criteria were: (1) patients with diabetes,
             successful in life?                              cancer, collagen disorders, deficiency status; (2) others
             You think your body   6 (20)  19 (63)  0.0001†   acute or chronical dermatological disorders; (3) patients
             is beautiful?
                                                              with coagulation defects and platelet count less than
            †: statistically significant; *: raw score ≥ 2; QoL-Q: questionnaire of   150,000/mm ; (4) pregnancy status; (5) acute phase of
                                                                         3
            quality of life
                                                              acne; and (6) chronical assumption of anti-aggregants
            CO 2  laser resurfacing for face atrophic scars by acne   agents or non-steroidal anti-inflammatory drugs.
            and to analyse patient’s satisfaction with our original
            questionnaire. All related patients are consented and   RESULTS
            agree with this publication.
                                                              Preoperative thickness of subcutaneous tissue of patients
            METHODS                                           from group A was 0.532 mm, whilst preoperative
                                                              thickness of subcutaneous tissue of patients from group B
            From March 2014 to June 2015, 30 patients with acne   was 0.737 mm. Postoperative thickness of subcutaneous
            scars on the cheeks were selected for this pilot study.   tissue was 1.201 mm in group A and 1.367 mm in group
            Age ranged between 18 and 52 years old. Patients   B. The improvement of thickness of subcutaneous tissue
            were evaluated pre- and postoperatively by a physical   was 0.668 mm in group A and 0.630 mm in group B.
            examination, photographs and ultrasound scan with a 22   Preoperative and postoperative thickness values of
            MHz probe to measure subcutaneous tissue thickness.   group A and group B are displayed in Tables 1 and 2,
                                                          [2]
            All patients were treated by infiltration of nanofat and PRP.    respectively. The difference in thickness obtained with the
            The production of PRP was achieved by RegenLab THT   treatment in group A and in group B was not statistically
                ®
            tube  method. [3,4]  Subsequently, patients were randomly   significant, with a P = 0.7289. Answers of QoL-Q pre-
            divided into 2 groups: group A, which also underwent   module and post-module questionnaires are reported in
            a fractional CO 2  laser resurfacing at 15 W; and group   Table 3 and Figure 4, respectively.
            B, which only underwent nanofat and PRP infiltration.
            Patients attended a 1 month, 3 months and 6 months   DISCUSSION
            follow-up after treatment. The difference in thickness
                                                                                                           [4-8]
            obtained with the treatment in group A and in group B   Currently, we have many new treatments for acne scars,
            was compared through a t-test on unpaired data. Our   no gold standard has been officially identified yet.
            original questionnaire of quality of life questionnaire   Historically, the most used treatments were: dermabrasion,
            (QoL-Q) was also administered pre- and postoperatively   a decade-old technique which employs the use of a
            to analyse satisfaction and aesthetical perception of the   motorised device equipped with an abrasive material to
            Plast Aesthet Res || Volume 3 || July 7, 2016                                                 237
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