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Figure 6: The case of a 36-year-old woman with boxcar acne scars,
                                                              treated with platelet-rich plasma and nanofat injection and laser CO 2 . (A)
            Figure 4: Student t-test for unpaired data. Pre-op: 8.818 ± 1.661, n =   preoperative situation; (B) 3 months after the second treatment
            11; post-op: 25.00 ± 0.8421, n = 11; P < 0.0001




























                                                              Figure 7: The case of a 41-year-old man with boxcar scars, treated with
                                                              platelet-rich plasma and nanofat injection. (A) preoperative situation; (B) 3
            Figure 5: The case of a 33-year-old woman with icepick scar treated   months after the second treatment
            with platelet-rich plasma and nanofat injection and laser CO 2 . (A)
            preoperative situation; (B) 3 months after the second treatment
                                                              augmentation, another effective treatment of superficial
            physically remove the superficial layers of the skin, thus   atrophic acne scars which is characterised by the
            inducing the wound-healing process with subsequent   injection of hyaluronic acid or calcium hydroxylapatite,
            formation of new collagen;  ablative lasers, which are   poly-L-lactic acid, or even autologous fat to replace lost
                                   [9]
                                               [10]
            effective in the treatment of atrophic scars;  nonablative   tissue volume while simultaneously inducing collagen
                                                                                                       [16]
            radiofrequency, which gives better results in the treatment   production via stretching of dermal fibroblasts.  The
            of ice pick scars, compared to the use in more superficial   idea of our protocol came from the patients’ request to
                 [11]
            scars;  subcision, a more physically intensive technique   search a satisfactory solution to the problem of atrophic
            useful for treatment of superficial atrophic acne scars;    scars of the face. These scars are not only the outcome
                                                         [12]
            skin needling, also referred to as collagen induction   of a devastating inflammatory disease for the patient’s
            therapy, which makes use of vertical needle punctures to   appearance, but in severe cases constitute the reason
                                    [13]
            treat rolling and boxcar scars;  punch techniques, useful   of relational and psychological problems. We think the
            for treating deeper atrophic acne scarring, which are   atrophic acne scars should be treated as “dips” to fill
            difficult to be treated otherwise;  chemical peels, which   and smooth. In fact, scars are found in the subcutaneous
                                       [14]
            traditionally employ acidic compounds to strip away the   tissue, thus making a decisive surface treatment difficult
            outer layers of skin at variable depths, depending on the   to obtain. Scars need also a stimulation to maintain
                                                [15]
            concentration of the agent being applied;  soft-tissue   that volume. The best treatment is to fill the scars and
            238                                                                 Plast Aesthet Res || Volume 3 || July 7, 2016
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