Page 86 - Read Online
P. 86
Topic: State of the Art in the Management of Oral Squamous Cell Carcinoma
State of the art in the management of oral
squamous cell carcinoma
Raúl González-García
Department of Oral and Maxillofacial-Head and Neck Surgery, University Hospital Infanta Cristina, 06080 Badajoz, Spain.
Correspondence Author: Prof. Raúl González-García, Department of Oral and Maxillofacial-Head and Neck Surgery, University Hospital
Infanta Cristina, 06080 Badajoz, Spain. E-mail: raulmaxilo@gmail.com
Dr. Raúl González-García, M.D., Ph.D, FEBOMFS, was graduated in Medicine (Medical Degree, M.D.) by the
Universidad Autónoma de Madrid School of Medicine, Madrid, Spain, in 2001, and obtained his trainee in
Oral and Maxillofacial Surgery in the University Hospital La Princesa, Madrid, Spain, in 2007. He obtained
his Ph.D. Degree in Medicine and Surgery at the Universidad Autónoma de Madrid School of Medicine, in
2011. Since 2007 he is Consultant Surgeon at the Department of Oral and Maxillofacial Surgery, University
Hospital Infanta Cristina, Badajoz, Spain, and he is also a University Honorary Collaborator at the Universidad
de Extremadura School of Medicine. He is actually Editor-in-Chief of Plastic and Aesthetic Research, Assistant
Director of Revista Española de Cirugía Oral y Maxilofacial, Permanent Member of the Reviewer Commitee of
International Journal of Oral and Maxillofacial Surgery, Contributing Editor of Current Research in Dentistry, and
Member of the Editorial Board/reviewer of more than 35 international journals of the speciality. He is author of
more than 130 publications, 96 of them in international Medline/PubMed-indexed journals, 15 chapters in books
of the speciality, and he is author of the text book "Reconstrucción Maxilomandibular Compleja: Microcirugía,
Distracción Ósea e Implantes dentales".
When considering the last report by the World Health The present editorial is an introductory paper to a special
Organization in 2014, oral squamous cell carcinoma issue composed of eleven manuscripts focusing on particular
(OSCC) represents the seventh cause of cancer worldwide aspects about the state of the art in OSCC under the light
and causes 529,000 new cases per year. In addition to its of current knowledge. While strict criteria for systematic
considerable frequency, death by this entity may overcome reviewing concerning Cochrane database recommendations
in approximately 50% of the patients, even after aggressive have not been followed due to the heterogeneity of the
multi-modality treatment. Although surgery followed or not revised series, an effort has been made to selectively
by radiotherapy is the main treatment option, many factors approach particular aspects of OSCC management, while
may influence overall outcome in terms of survival, including selecting the most prominent series within the last 15 years.
patient-related, tumor-related and treatment-related factors. Some of the incoming works have made a special effort in
trying to include and systematically analyze more relevant
works according to a predetermined search, inclusion and
A myriad of articles has been published in the literature exclusion criteria, with a particular PICO question and a flow
concerning “oral cancer” and “squamous cell carcinoma chart, while others have made a general review according
of the oral cavity and oropharynx”. Although several high- to subjective criteria based on authors’ own experience in
quality papers are advised, the heterogeneity of the studies selecting more relevant works. While the more systematically
in terms of methodology, treatment protocols, and inclusion/ approach is more relevant in the evidence-based scale,
exclusion criteria makes direct comparison among series reviews by selected experts still have a relevant role in the
and institutions challenging. However, some main guidelines field of surgery.
may guide the clinician into the best treatment modality for
each patient, while an effort in terms of classifying patients The approached items were: (1) the role of human
who may benefit from one or other treatment option has This is an open access article distributed under the terms of the Creative Commons
been made in the last decade. Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix,
tweak and build upon the work non-commercially, as long as the author is credited
Access this article online and the new creations are licensed under the identical terms.
Quick Response Code:
Website: For reprints contact: service@oaepublish.com
http://www.parjournal.net
How to cite this article: González-García R. State of the art in the
management of oral squamous cell carcinoma. Plast Aesthet Res
DOI:
10.20517/2347-9264.2016.30 2016;3:129-31.
Received: 20-04-2016; Accepted: 04-05-2016
© 2016 Plastic and Aesthetic Research | Published by OAE Publishing Inc. 129