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Topic: State of the Art in the Management of Oral Squamous Cell Carcinoma




           State of the art in the management of oral

           squamous cell carcinoma





           Raúl González-García

           Department of Oral and Maxillofacial-Head and Neck Surgery, University Hospital Infanta Cristina, 06080 Badajoz, Spain.
           Correspondence Author: Prof. Raúl González-García, Department of Oral and Maxillofacial-Head and Neck Surgery, University Hospital
           Infanta Cristina, 06080 Badajoz, Spain. E-mail: raulmaxilo@gmail.com
                               Dr. Raúl González-García, M.D., Ph.D, FEBOMFS, was graduated in Medicine (Medical Degree, M.D.) by the
                               Universidad Autónoma de Madrid School of Medicine, Madrid, Spain, in 2001, and obtained his trainee in
                               Oral and Maxillofacial Surgery in the University Hospital La Princesa, Madrid, Spain, in 2007. He obtained
                               his Ph.D. Degree in Medicine and Surgery at the Universidad Autónoma de Madrid School of Medicine, in
                               2011. Since 2007 he is Consultant Surgeon at the Department of Oral and Maxillofacial Surgery, University
                               Hospital Infanta Cristina, Badajoz, Spain, and he is also a University Honorary Collaborator at the Universidad
                               de Extremadura  School of Medicine. He is actually Editor-in-Chief of Plastic and Aesthetic Research, Assistant
                               Director of Revista Española de Cirugía Oral y Maxilofacial, Permanent Member of the Reviewer Commitee of
                               International Journal of Oral and Maxillofacial Surgery, Contributing Editor of Current Research in Dentistry, and
                               Member of the Editorial Board/reviewer of more than 35 international journals of the speciality. He is author of
                               more than 130 publications, 96 of them in international Medline/PubMed-indexed journals, 15 chapters in books
                               of the speciality, and he is author of the text book "Reconstrucción Maxilomandibular Compleja: Microcirugía,
                               Distracción Ósea e Implantes dentales".


           When considering  the last report by  the World Health   The present editorial is an introductory paper to a special
           Organization  in 2014, oral squamous  cell carcinoma   issue composed of eleven manuscripts focusing on particular
           (OSCC) represents the seventh cause of cancer worldwide   aspects about the state of the art in OSCC under the light
           and causes 529,000 new cases per year. In addition to its   of current knowledge. While strict criteria for systematic
           considerable frequency, death by this entity may overcome   reviewing concerning Cochrane database recommendations
           in approximately 50% of the patients, even after aggressive   have not been followed  due to the heterogeneity of the
           multi-modality treatment. Although surgery followed or not   revised series,  an effort has been made to selectively
           by radiotherapy is the main treatment option, many factors   approach particular  aspects of  OSCC  management,  while
           may influence overall outcome in terms of survival, including   selecting the most prominent series within the last 15 years.
           patient-related, tumor-related and treatment-related factors.  Some of the incoming works have made a special effort in
                                                               trying to include and systematically analyze more relevant
                                                               works according to a predetermined search, inclusion and
           A myriad of articles has been  published in  the  literature   exclusion criteria, with a particular PICO question and a flow
           concerning “oral  cancer”  and “squamous  cell carcinoma   chart, while others have made a general review according
           of the oral cavity and oropharynx”. Although several high-  to subjective criteria based on authors’ own experience in
           quality papers are advised, the heterogeneity of the studies   selecting more relevant works. While the more systematically
           in terms of methodology, treatment protocols, and inclusion/  approach is more relevant in the evidence-based scale,
           exclusion criteria  makes  direct comparison among  series   reviews by selected experts still have a relevant role in the
           and institutions challenging. However, some main guidelines   field of surgery.
           may guide the clinician into the best treatment modality for
           each patient, while an effort in terms of classifying patients   The approached  items  were: (1)  the role of human
           who may benefit from one or other treatment option has   This is an open access article distributed under the terms of the Creative Commons
           been made in the last decade.                       Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix,
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                                                                How to cite this article: González-García R. State of the art in the
                                                                management of oral squamous cell carcinoma. Plast Aesthet Res
                                    DOI:
                                    10.20517/2347-9264.2016.30  2016;3:129-31.
                                                                Received: 20-04-2016; Accepted: 04-05-2016
           © 2016 Plastic and Aesthetic Research | Published by OAE Publishing Inc.                           129
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