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Figure 2: Selective supraomohioid neck dissection involving cervical levels
         Figure 1: Oral squamous cell carcinoma (OSCC) of the tongue. (A) Intraoral   I to III in a T1 oral squamous cell carcinoma of the tongue. (A) Intraoral
         view of the tumor; (B) immediate intraoperative tissue shrinkage following   view of the tumor; (B) intraoperative view of the dissected neck
         resection of OSCC by a partial glossectomy











         Figure 3: Oral squamous cell carcinoma of the upper maxilla. (A) Intraoral
         view of the tumor; (B) intraoperative view of the remnant maxilla following
         anterior partial maxillectomy

         papillomavirus (HPV) in OSCC; (2) the role of sentinel node
         biopsy in the treatment of OSCC; (3) the influence of surgical
         resection margins in OSCC; (4) the role of radiotherapy in
         OSCC; (5) the role of elective neck dissection in early-staged   Figure 4: Contralateral modified type III radical neck dissection in
         OSCC; (6) the role of elective neck dissection in OSCC of the   an oral squamous cell carcinoma of the mandible involving the right
                                                             parasymphiseal region. Detail of levels II to V left neck dissection
         upper maxilla; (7) the role of contralateral neck dissection
         in OSCC; (8) the role of salvage surgery in recurrent OSCC;   elsewhere named “Iberic graft”, a new technique consisting
         (9) the reliability of the combined-triangular full-thickness   on the use of full-thickness skin grafts obtained from the
         skin graft for covering the radial forearm free flap donor-  volar side of the forearm skin.
         site; (10) the prognosis and quality of life in head and neck
         cancer; and (11) last but not least a special article about  the   Some strong conclusions can be obtained from the reading
         current role of the facial allograft transplantation. This last   of the reviewing works included in this special issue, which
         paper is performed by one of the first and more experienced   may  move  the  reader  closer to  the  current  knowledge
         surgical teams in performing facial allograft transplantation   about OSCC, or at least may provide a baseline from which
         worldwide.                                          the reader can deep into a more specific and advanced
                                                             knowledge. These conclusions are: (1) HPV is increasingly
         Electronic literature  search was conducted mostly  in   being associated to OSCC, usually diagnosed at a younger
         Medline, but also Embase  and Cochrane databases were   age, mainly in the oropharynx, while HPV  OSCC patients
                                                                                                 +
         used in some of the articles in the present issue. The   have an increased survival, better treatment response and
         abstracts of yielded results were reviewed and the full text of   lower recurrence rates; (2)  the sentinel  node biopsy is a
         those with apparent relevance was obtained. The references   reliable staging method in early-stage OSCC as an alternative
         of identified  articles  were  crosschecked for unidentified   to elective neck dissection for staging  N0-neck, with  a
         articles, and only those in English language were selected.   reasonable  false-negative  rate  while  decreasing  morbidity
         In most of the articles in the present issue,  exclusion   associated to selective neck dissection if performed by an
         criteria concerning the type of articles to be included were   experienced multidisciplinary  team;  (3) tissue  shrinkage
         established, thus excluding case reports and technical notes,   on surgical margins of resection in OSCC is a tangible
         letters to Editors, expert opinions, animal or in vitro studies,   phenomenon,  being  the  highest  percentage  of retraction
         review articles, and repetitive data from series of the same   occurring at the time of resection, which leads the surgeon
         authors or institutions.  Qualitative systematic  reviews  or   into a major therapeutic role, as involved or closed margins
         non-systematic reviews were performed, while two articles,   in the histologic report may determine the administration
         one concerning elective neck  dissection in OSCC of the   of complementary treatments such as post-operative
         upper maxilla, and the other dealing with salvage surgery for   radiotherapy and/or chemotherapy [Figure  1]; (4) both
         OSCC, analyzed data from features in the selected articles to   external radiotherapy and brachytherapy play a determinant
         infer new results as meta-analysis. Two additional articles   role  in  the  treatment  of OSCC,  alone in  early  stages  or
         are dealing with special reconstructive surgical procedures   combined  with  surgery  and/or  chemotherapy  in  advanced
         that were developed  and put in practice  by the authors'   ones; (5) if routine strict follow-up using ultra-sonography
         surgical teams, being the facial allograft transplantation and   fine needle aspiration citology (USgFNAC) by a well-trained
         the covering of the radial forearm free flap donor-site by the   ultrasonographer cannot be  assured  in  clinically N0-neck,
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