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Li et al. Sparganosis of the brain

surgical removal of the sparganosis from the infested Critically revising the article: Q. Xie
site of the brain. Both stereotactic aspiration and an Reviewed submitted version of manuscript: X.C.
opening craniotomy were used by neurosurgeons. The Chen, Y. Gong
goal of surgery is to completely remove the granuloma Approved the final version of the manuscript on behalf
along with the larval. Deng et al. [26] reported a series of all authors: Q. Xie, Y. Gong
of 11 cases who underwent stereotactic aspiration Statistical analysis: H.X. Li, S.H. Luan
surgeries, complete removal as achieved in 10 patients Administrative/technical/material support: X.H. Chen
while incomplete removal in 1 patient. Due to the small Study supervision: Q. Xie, Y. Gong
wounds, stereotactic aspiration is recommended by
most neurosurgeons. In the 26 cerebral sparganosis Financial support and sponsorship
[18]
cases of Hong et al. , 16 of them were treated with This study was supported by grants from the National
craniotomy, 7 of them were treated with stereotactic Natural Science Foundation of China (81372707 to Y.
aspiration and another 3 were treated with praziquantel Gong) and the Science and Technology Commission
only. None of them experienced a relapse of the of Shanghai Municipality (16140903000 to Y. Gong
[13]
disease. Yu et al. reported in 8 of 9 cases of cerebral and 15140902200 to H.L. Tang).
sparganosis patients underwent a craniotomy due to
lack of stereotactic equipment, with 1 patient dying due Conflicts of interest
There are no conflicts of interest.
to unspecified reason. Both investigators reported that
symptom duration more than one year indicated worse Patient consent
prognosisafter surgery [13,18] . In our case, we used a Informed consent was obtained from the patient
navigation guided craniotomy to resect the granuloma included in the study (KY-2012-019).
as well as the peri-lesion glia proliferation zone. The
symptoms resolved immediately after surgery, the patient Ethics approval
was administrated AED medication and 5 mg/day of All procedures performed in studies involving human
praziquantel for 3 months. After 6-month follow-up, the participants were in accordance with the ethical
patient was well without further seizures. standards of Huashan Hospital, Fudan University
and with the 1964 Helsinki declaration and its later
Cerebral sparganosis is a neglected food borne zoonosis amendments or comparable ethical standards.
and since it has no specific clinical characteristic, it is
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