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Chen et al. Characteristics of viral encephalitis with epilepsy
disturbance in the acute phase is severer than for 4. Shen YQ. Application value analysis of EEG in the diagnosis of viral
other patients. Therefore, this study suggests taking encephalitis. Chin Mod Med 2015;5:96-7, 100.
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active antiepileptic treatment for patients with frequent 5. Peng J, Luo TY, Lu FJ, Ouyang Y, Fang WD, Wu JQ. MRI, DWI
and 1H-MRS features of viral encephalitis: report of 36 cases. Acta
seizures. As we lack follow-up investigation of viral Academiae Medicinae Militaris Tertiae 2009;3:257-60.
encephalitis patients after discharge, we are unable to 6. Qiao XH, Tong MQ, Yang F, Wang J, Ding CY. Research status of viral
determine which AEDs have definite advantage over encephalitis complicated with epilepsy. Chin J Clinicians (Electronic
the others. The subject of viral encephalitis complicated Edition) 2012;11:3025-8. (in Chinese)
with epilepsy remains for further study. 7. Misra UK, Kalita J. Seizures in encephalitis: predictors and outcome.
Seizure 2009;18:583-7.
Authors’ contributions 8. Singh TD, Fugate JE, Hocker SE, Rabinstein AA. Postencephalitic
epilepsy: clinical characteristics and predictors. Epilepsia
Concept: S.Y. Chen, W. Ma, Y.Y. Chen, X.W. Fan 2015;56:133-8.
Design: S.Y. Chen, X.W. Fan 9. Huang D, Huang YL, Liu T. Clinical characteristics of viral
Literature search: S.Y. Chen, W. Ma, Y.Y. Chen encephalitis patients with secondary epilepsy. Chin Tropical Med
Data analysis: S.Y. Chen 2014;4:486-7, 495.
Manuscript preparation: S.Y. Chen, X.W. Fan 10. Gong SH, Cao ZH, Song JH. On examination of cerebrospinal fluid of
viral encephalitis patients. J Brain Nerv Dis 2008;6:694-6.
Manuscript editing: S.Y. Chen, X.W. Fan 11. Feng YK. Clinical Electroencephalography. Beijing: People’s Medical
Manuscript review: S.Y. Chen, X.W. Fan Publishing House; 1980. p. 62-4.
12. Whitley RJ, Gnann JW. Viral encephalitis: familiar infections and
Financial support and sponsorship emerging pathogens. Lancet 2002;359:507-13.
None. 13. Kuramoto T, Daikoku T, Yoshida Y, Takemoto M, Oshima K, Eizuru Y,
Kanda Y, Miyawaki T, Shiraki K. Novel anticytomegalovirus activity
Conflicts of interest of immunosuppressant mizorihine and its synergism with ganciclovir.
There are no conflicts of interest. J Pharmacol Exp Ther 2010;333:816-21.
14. Dong YP. Clinical observation of methylpredinsolone combined with
Patient consent immunoglobulin in the treatment of severe viral encephalitis. Clin
Med 2014;5:20-1.
Patient consent was obtained for publishing this work. 15. Zhen HJ, Qiu YQ, Zhu PQ. Clinical analysis of 431 cases of central
nervous system infection. Chin J Infectious Dis 2006;3:190-1.
Ethics approval 16. Usha KM, Chong T, Jayantee K. Viral encephalitis and epilepsy.
Ethics committee approval was obtained for publishing Epilepsia 2008;49:S13.
this work. 17. Shao DB,Sun HC. Clinical progress of viral encephalitis. Chin Gen
Pract 2008;20:1817-9.
18. Ai TM. Analysis of prognostic factors in 67 patients with viral
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