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Schindler et al. Microparticles in neuroimmune signaling

increase microglial mRNA expression of TNF-α and IL- Patient consent
1β. Use of an MCP-1 neutralizing antibody decreased No patients involved.
MCP-1 induced upregulated microglial expression of
these pro-inflammatory mediators and also attenuated Ethics approval
MCP-1 induced neuronal death in neuron/microglia co- This article does not contain any studies with human
cultures. Accordingly, these properties of MCP-1 may participants or animals.
[58]
provide an explanation for MP-mediated THP-1 cell
toxicity towards SH-SY5Y neuronal cells. REFERENCES

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Conflict of interest 19. Gyorgy B, Szabó TG, Pásztói M, Pál Z, Misják P, Aradi B, László V,
There are no conflicts of interest. Pállinger E, Pap E, Kittel A, Nagy G, Falus A, Buzás EI. Membrane
240 Neuroimmunology and Neuroinflammation ¦ Volume 3 ¦ October 28, 2016