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special thanks to Dr. Raffaele Iorio for providing the pictures 16. Petit-Pedrol M, Armangue T, Peng X, Bataller L, Cellucci T, Davis R,
included in Figure 2. McCracken L, Martinez-Hernandez E, Mason WP, Kruer MC, Ritacco
DG, Grisold W, Meaney BF, AlcaláC, Sillevis-Smitt P, Titulaer MJ, Balice-
Gordon R, Graus F, Dalmau J. Encephalitis with refractory seizures,
Financial support and sponsorship status epilepticus, and antibodies to the GABAA receptor: a case series,
Nil. characterization of the antigen, and analysis of the effects of antibodies.
Lancet Neurol 2014;13:276-86.
Conflicts of interest 17. Dalmau J, Gleichman AJ, Hughes EG, Rossi JE, Peng X, Lai M, Dessain
SK, Rosenfeld MR, Balice-Gordon R, Lynch DR. Anti-NMDA-receptor
There are no conflicts of interest. encephalitis: case series and analysis of the effects of antibodies. Lancet
Neurol 2008;7:1091-8.
REFERENCES 18. Titulaer MJ, McCracken L, Gabilondo I, Armangué T, Glaser C, Iizuka
T, Honig LS, Benseler SM, Kawachi I, Martinez-Hernandez E, Aguilar
E, Gresa-ArribasN, Ryan-Florance N, Torrents A, Saiz A, Rosenfeld MR,
1. Iorio R, Lennon VA. Neuralantigen-specific autoimmune disorders. Balice-Gordon R, Graus F, Dalmau J. Treatment and prognostic factors for
Immunol Rev 2012;248:104-21. long-term outcome in patients with anti-NMDA receptor encephalitis: an
2. Armangue T, Petit-Pedrol M, Dalmau J. Autoimmune encephalitis in observational cohort study. Lancet Neurol 2013;12:157-65.
children. J Child Neurol 2012;27:1460-9. 19. Viaccoz A, Desestret V, Ducray F, Picard G, Cavillon G, Rogemond
3. Iorio R, Damato V, Mirabella M, Vita MG, Hulsenboom E, Plantone D, V, Antoine JC, Delattre JY, Honnorat J. Clinical specificities of adult
Bizzarro A, Del Grande A, Sillevis Smitt PA. Cerebellar degeneration male patients with NMDA receptor antibodies encephalitis. Neurology
associated with mGluR1 autoantibodies as a paraneoplastic manifestation 2014;82:556-63.
of prostate adenocarcinoma. J Neuroimmunol 2013;263:155-8. 20. Gresa-Arribas N, Titulaer MJ, Torrents A, Aguilar E, McCracken L, Leypoldt
4. Lancaster E, Lai M, Peng X, Hughes E, Constantinescu R, Raizer J, F, Gleichman AJ, Balice-Gordon R, Rosenfeld MR, Lynch D, GrausF,
Friedman D, Skeen MB, Grisold W, Kimura A, Ohta K, Iizuka T, Guzman M, Dalmau J. Antibody titers at diagnosis and during follow-up of anti-NMDA
Graus F, Moss SJ, Balice-Gordon R, Dalmau J. Antibodies to the GABA(B) receptor encephalitis: a retrospective study. Lancet Neurol 2014;13:167-77.
receptor in limbic encephalitis with seizures: case series and characterization 21. Zandi MS, Paterson RW, Ellul MA, Jacobson L, Al-Diwani A, Jones JL, Cox
of the antigen. Lancet Neurol 2010;9:67-76. AL, Lennox B, Stamelou M, Bhatia KP, Schott JM, Coles AJ, Kullmann DM,
5. Ohkawa T, Satake S, Yokoi N, Miyazaki Y, Ohshita T, Sobue G, Takashima Vincent A. Clinical relevance of serum antibodies to extracellular N-methyl-
H, Watanabe O, Fukata Y, Fukata M. Identification and characterization of aspartate receptor epitopes. J Neurol Neurosurg Psychiatry 2015;86:708-13.
GABA(A) receptor autoantibodies in autoimmune encephalitis. J Neurosci 22. Dahm L, Ott C, Steiner J,Stepniak B, Teegen B, Saschenbrecker S,
2014;34:8151-63. Hammer C, Borowski K, Begemann M, Lemke S, Rentzsch K, Probst C,
6. Lai M, Huijbers M.G, Lancaster E, Graus F, Bataller L, Balice-Gordon Martens H, Wienands J, Spalletta G, Weissenborn K, Stöcker W, Enrenreich
R, Cowell JK, Dalmau J. Investigation of LGI1 as the antigen in limbic H. Seroprevalence of autoantibodies against brain antigens in health and
encephalitis previously attributed to potassium channels: a case series. disease. Ann Neurol 2014;76:82-94.
Lancet Neurol 2010;9:776-85. 23. Steiner J, Teegen B, Schiltz K, Bernstein HG, Stoecker W, Bogerts B.
7. Panzer JA, Dale RC. Anti-AMPA receptor encephalitis: the family Prevalence of N-methyl-D-aspartate receptor autoantibodies in the
of glutamatergic autoencephalitides further expands. Neurology peripheral blood: healthy control samples revisited. JAMA Psychiatry
2015;84:2390-1. 2014;71:838-9.
8. Kuppuswamy PS, Takala CR, Sola CL. Management of psychiatric 24. McKeon A, Pittock SJ. Paraneoplastic encephalomyelopathies: pathology
symptoms in anti-NMDAR encephalitis: a case series, literature review and and mechanisms. Acta Neuropathol 2011;122:381-400.
future directions. Gen Hosp Psychiatry 2014;36:388-91. 25. Graus F, Dalmau J. Paraneoplastic neurological syndromes. Curr Opin
9. Titulaer MJ, Dalmau J. Seizures as first symptom of anti-NMDA receptor Neurol 2012;25:795-801.
encephalitis are more common in men. Neurology 2014;82:550-1. 26. Lancaster E, Dalmau J. Neuronal autoantigens-pathogenesis, associated
10. Sabater L, Gaig C, Gelpi E, Bataller L, Lewerenz J, Torres-Vega E, disorders and antibody testing. Nat Rev Neurol 2012;8:380-90.
Contreras A, Giometto B, Compta Y, Embid C, Vilaseca I, Iranzo A, 27. Titulaer MJ, Soffietti R, Dalmau J, Gilhus NE, Giometto B, Graus F, Grisold
Santamaría J, Dalmau J, Graus F. A novel non-rapid-eye movement and W, Honnorat J, Sillevis Smitt PA, Tanasescu R, Vedeler CA, Voltz R,
rapid-eye-movement parasomnia with sleep breathing disorder associated Verschuuren JJ. European Federation of Neurological Societies. Screening
with antibodies to IgLON5: a case series, characterization of the antigen, for tumours in paraneoplastic syndromes: report of an EFNS task force. Eur
and post-mortem study. Lancet Neurol 2014;13:575-86. J Neurol 2011;18:19-e3.
11. Boronat A, Gelfand JM, Gresa-Arribas N, Jeong HY, Walsh M, Roberts K, 28. Iorio R, Assenza G, Tombini M, Colicchio G, Della Marca G, Benvenga A,
Martinez-Hernandez E, Rosenfeld MR, Balice-Gordon R, Graus F, Rudy Damato V, Rossini PM, Vollono C, Plantone D, Marti A, Batocchi AP, Evoli
B, Dalmau J. Encephalitis and antibodies to dipeptidyl-peptidase-like A. The detection of neural autoantibodies in patients with antiepileptic-
protein-6, a subunit of Kv4.2 potassium channels. Ann Neurol 2013;73:120- drug-resistant epilepsy predicts response to immunotherapy. Eur J Neurol
8. 2015;22:70-8.
12. Malter MP, Elger CE, Surges R. Diagnostic value of CSF findings in antibody- 29. Armangue T, Leypoldt F, Malaga I, Raspall-Chaure M, Marti I, Nichter
associated limbic and anti-NMDAR-encephalitis. Seizure 2013;22:136-40. C, Pugh J, Vicente-Rasoamalala M, Lafuente-Hidalgo M, Macaya A,
13. Jarius S, Hoffmann L, Clover L, Vincent A, Voltz R. CSF findings in Ke M, Titulaer MJ, Höftberger R, Sheriff H, Glaser C, Dalmau J. Herpes
patients with voltagegated potassium channel antibody associated limbic simplex virus encephalitis is a trigger of brain autoimmunity. Ann Neurol
encephalitis. J Neurol Sci 2008;268:74-7. 2014;75:317-23.
14. Schmitt SE, Pargeon K, Frechette ES, Hirsch LJ, Dalmau J, Friedman 30. Titulaer MJ, Hoftberger R, Iizuka T, Leypoldt F, McCracken L, Cellucci T,
D. Extreme delta brush: a unique EEG pattern in adults with anti-NMDA Benson LA, Shu H, Irioka T, Hirano M, Singh G, CoboCalvo A, Kaida K,
receptor encephalitis. Neurology 2012;79:1094-100. Morales PS, Wirtz PW, Yamamoto T, Reindl M, Rosenfeld MR, Graus F, Saiz
15. Armangue T, Leypoldt F, Dalmau J. Autoimmune encephalitis as differential A, Dalmau J. Overlapping demyelinating syndromes and anti-N-methyl-D-
diagnosis of infectious encephalitis. Curr Opin Neurol 2014;27:361-8. aspartate receptor encephalitis. Ann Neurol 2014;75:411-28.
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