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De Aquino et al. Mini-invasive Surg 2017;1:167-72                  Mini-invasive Surgery
           DOI: 10.20517/2574-1225.2017.29
                                                                                                www.misjournal.net
            Topic: Achalasia Management: the South American viewpoint                           Open Access


           Non-conventional surgical approach

           to achalasia: mucosectomy and

           endomuscular pull-through




           Jose Luis Braga De Aquino, Marcelo Manzano Said, José Gonzaga Teixeira De Camargo
           Department of Surgery, Medical School, Catholic University at Campinas, Campinas, SP 13015-192, Brazil.

           Correspondence to: Dr. Jose Luis Braga De Aquino, Department of Surgery, Medical School, Catholic University at Campinas, Boaventurado Amaral, 1190,
           ap. 12-CEP, Campinas, SP 13015-192, Brazil. E-mail: jlaquino@sigmanet.com.br

           How to cite this article: De Aquino JLB, Said MM, De Camargo JGT. Non-conventional surgical approach to achalasia: mucosectomy and endomuscular
           pull-through. Mini-invasive Surg 2017;1:167-72.

                                         ABSTRACT
            Article history:              Aim:  Transhiatal esophagectomy  is  a  therapeuthic  option for  the treatment  of end-stage
            Received: 27 Jul 2017         achalasia that avoids the complications of a thoracotomy. This technique; however, is still
            First Decision: 10 Aug 2017   linked to some degree of morbimortality especially due to pleuromediastinal complications.
            Revised: 1 Oct 2017           Esophageal mucosectomy and endomuscular pull-through could avoid these complications.
            Accepted: 14 Oct 2017         This study aims to evaluate the short and long-term outcomes of esophageal mucosectomy and
            Published: 28 Dec 2017        endomuscular pull-through in a series of patients with advanced megaesophagus. Methods:
                                          We retrospectively studied 115 patients with end-stage achalasia that underwent esophageal
            Key words:                    mucosectomy and endomuscular pull-through. Digestive tract reconstruction was accomplished
            Achalasia,                    most times using the stomachthourgh the muscular tunnel. Outcomes were evaluated in a short
            esophagectomy,                and long-term follow-up based on clinical, endoscopic and tomographic evaluation. Results:
            megaesophagus,                Anastomotic leak or stenosis was present in 27%. Pleural efusion was noticed in 11% and
            mucosectomy                   pneumonia in 9%. Mortality was 1.7%. Long-term follow-up (over 10 years) was possible in 42
                                          patients. Excellent and good clinical results were obtained in 83% of the patients. Conclusion:
                                          Esophageal mucosectomy  and endomuscular pull-through  is a  valuable procedure for the
                                          treatment of end-stage achalasia. It shows a low rate of complications and good outcomes at
                                          long-term follow-up.


           INTRODUCTION                                       Different  approaches  have  been  proposed  to
                                                              treat this disease, such as endoscopic dilatation,
           Idiopathic and chagasic achalasia have different   esophageal caliber-reducing operations, operations
           etiology but, apart from this fact, both diseases   on the diaphragm or esophageal extrinsic innervation,
           share the same clinical, radiologic, endoscopic and   cardiectomy, cardioplasties, transthoracic and
           manometric presentations. Thus, any therapeutic    transhiatal  esophagectomy. Neither  treatment;
           modality may be applied equality irrespective of   however, seems to be ideal since they do not act
           etiology.                                          directly on the physiopathology of the disease [1-5] .


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