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Bhardwaj                                                                                                                                                                                       MicroRNAs in atopic dermatitis

               cells regulates tissue inflammation by producing interleukin 17. Nat   29.  Wei T, Orfanidis K, Xu N, Janson P, Ståhle M, Pivarcsi A, Sonkoly E.
               Immunol 2005;6:1133-41.                           The expression of microRNA-203 during human skin morphogenesis.
           9.   Koga C, Kabashima K, Shiraishi N, Kobayashi M, Tokura Y. Possible   Exp Dermatol 2010;19:854-6.
               pathogenic role of Th17 cells for atopic dermatitis. J Invest Dermatol   30.  Faraoni I, Antonetti FR, Cardone J, Bonmassar E. miR-155 gene:
               2008;128:2625-30.                                 a typical multifunctional microRNA.  Biochim Biophys Acta
           10.  Peric M, Koglin S, Dombrowski Y, Gross K, Bradac E, Büchau A,   2009;1792:497-505.
               Steinmeyer A, Zügel U, Ruzicka T, Schauber J. Vitamin D analogs   31.  Thai TH, Calado DP, Casola S, Ansel KM, Xiao C, Xue Y, Murphy
               differentially control antimicrobial peptide/”alarmin” expression in   A, Frendewey D, Valenzuela D, Kutok JL, Schmidt-Supprian M,
               psoriasis. PLoS One 2009;4:e6340.                 Rajewsky N, Yancopoulos G, Rao A, Rajewsky K. Regulation of the
           11.  Toda  M, Leung DY, Molet S, Boguniewicz M,  Taha R,   germinal center response by microRNA-155. Science 2007;316:604-8.
               Christodoulopoulos P, Fukuda T, Elias JA, Hamid QA. Polarized in   32.  Rodriguez A, Vigorito E, Clare S, Warren MV, Couttet P, Soond DR,
               vivo expression of IL-11 and IL-17 between acute and chronic skin   van Dongen S, Grocock RJ, Das PP, Miska EA, Vetrie D, Okkenhaug
               lesions. J Allergy Clin Immunol 2003;111:875-81.  K, Enright AJ, Dougan G, Turner M, Bradley A. Requirement of bic/
           12.  Trifari S, Kaplan CD, Tran EH, Crellin NK, Spits H. Identification   microRNA-155 for normal immune function. Science 2007;316:608-
               of a human helper T cell population that has abundant production of   11.
               interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells. Nat   33.  Banerjee A, Schambach F, DeJong CS, Hammond SM, Reiner SL.
               Immunol 2009;10:864-71.                           Micro-RNA-155 inhibits IFN-gamma signaling in CD4+ T cells. Eur J
           13.  Nograles KE, Zaba LC, Shemer A, Fuentes-Duculan J, Cardinale I,   Immunol 2010;40:225-31.
               Kikuchi T, Ramon M, Bergman R, Krueger JG, Guttman-Yassky E.   34.  Sonkoly E, Janson P, Majuri ML, Savinko T, Fyhrquist N, Eidsmo L,
               IL-22-producing “T22” T cells account for upregulated IL-22 in atopic   Xu N, Meisgen F, Wei T, Bradley M, Stenvang J, Kauppinen S, Alenius
               dermatitis despite reduced IL-17-producing TH17 T cells. J Allergy   H, Lauerma A, Homey B, Winqvist O, Ståhle M, Pivarcsi A. MiR-155
               Clin Immunol 2009;123:1244-52.e2.                 is overexpressed in patients with atopic dermatitis and modulates T-cell
           14.  Nograles KE, Zaba LC, Guttman-Yassky E, Fuentes-Duculan J, Suárez-  proliferative responses by targeting cytotoxic T lymphocyte-associated
               Fariñas M, Cardinale I, Khatcherian A, Gonzalez J, Pierson KC, White   antigen 4. J Allergy Clin Immunol 2010;126:581-9.e1-20.
               TR, Pensabene C, Coats I, Novitskaya I, Lowes MA, Krueger JG. Th17   35.  Sonkoly E, Pivarcsi A. Advances in microRNAs: implications for
               cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory   immunity and inflammatory diseases. J Cell Mol Med 2009;13:24-38.
               and keratinocyte-response pathways. Br J Dermatol 2008;159:1092-  36.  Hellings PW, Vandenberghe P, Kasran A, Coorevits L, Overbergh
               102.                                              L, Mathieu C, Ceuppens JL. Blockade of CTLA-4 enhances allergic
           15.  Irvine AD, McLean WH, Leung DY. Filaggrin mutations associated   sensitization and eosinophilic airway inflammation in genetically
               with skin and allergic diseases. N Engl J Med 2011;365:1315-27.  predisposed mice. Eur J Immunol 2002;32:585-94.
           16.  McAleer MA, Irvine AD. The multifunctional role of filaggrin in   37.  Abrams JR, Lebwohl MG, Guzzo CA, Jegasothy BV, Goldfarb
               allergic skin disease. J Allergy Clin Immunol 2013;131:280-91.  MT, Goffe BS, Menter A, Lowe NJ, Krueger G, Brown MJ, Weiner
           17.  Mohiuddin MS, Ramamoorthy P, Reynolds PR, Curran-Everett D,   RS, Birkhofer MJ, Warner GL, Berry KK, Linsley PS, Krueger
               Leung DY. Increased compound heterozygous filaggrin mutations in   JG, Ochs HD, Kelley SL, Kang S. CTLA4Ig-mediated blockade of
               severe atopic dermatitis in the United States. J Allergy Clin Immunol   T-cell costimulation in patients with psoriasis vulgaris. J Clin Invest
               Pract 2013;1:534-6.                               1999;103:1243-52.
           18.  Samuelov L, Sprecher E. Peeling off the genetics of atopic dermatitis-  38.  Taganov KD, Boldin MP, Chang KJ, Baltimore D. NF-kappaB-
               like congenital disorders. J Allergy Clin Immunol 2014;134:808-15.  dependent induction of microRNA miR-146, an inhibitor targeted to
           19.  Kuo IH, Yoshida T, De Benedetto A, Beck LA. The cutaneous innate   signaling proteins of innate immune responses. Proc Natl Acad Sci U S
               immune response in patients with atopic dermatitis. J Allergy Clin   A 2006;103:12481-6.
               Immunol 2013;131:266-78.                       39.  Guttman-Yassky  E,  Nograles  KE,  Krueger  JG.  Contrasting
           20.  Rebane A, Akdis CA. MicroRNAs: Essential players in the regulation   pathogenesis of atopic dermatitis and psoriasis--part II: immune
               of inflammation. J Allergy Clin Immunol 2013;132:15-26.  cell subsets and therapeutic concepts. J Allergy Clin Immunol
           21.  Makeyev EV, Maniatis T. Multilevel regulation of gene expression by   2011;127:1420-32.
               microRNAs. Science 2008;319:1789-90.           40.  Boldin MP, Baltimore D. MicroRNAs, new effectors and regulators of
           22.  Sonkoly E, Ståhle M, Pivarcsi A. MicroRNAs: novel regulators in skin   NF-κB. Immunol Rev 2012;246:205-20.
               inflammation. Clin Exp Dermatol 2008;33:312-5.  41.  Etzrodt M, Cortez-Retamozo V, Newton A, Zhao J, Ng A, Wildgruber
           23.  Lu TX, Rothenberg ME. Diagnostic, functional, and therapeutic roles   M, Romero P, Wurdinger T, Xavier R, Geissmann F, Meylan E,
               of microRNA in allergic diseases. J Allergy Clin Immunol 2013;132:3-  Nahrendorf M, Swirski FK, Baltimore D, Weissleder R, Pittet MJ.
               13; quiz 4.                                       Regulation of monocyte functional heterogeneity by miR-146a and
           24.  Rebane A. microRNA and allergy. Adv Exp Med Biol 2015;888:331-52.  Relb. Cell Rep 2012;1:317-24.
           25.  Yi R, O’Carroll D, Pasolli HA, Zhang Z, Dietrich FS, Tarakhovsky   42.  Crone SG, Jacobsen A, Federspiel B, Bardram L, Krogh A, Lund AH,
               A, Fuchs E. Morphogenesis in skin is governed by discrete sets of   Friis-Hansen L. microRNA-146a inhibits G protein-coupled receptor-
               differentially expressed microRNAs. Nat Genet 2006;38:356-62.  mediated activation of NF-κB by targeting CARD10 and COPS8 in
           26.  Sonkoly E, Wei T, Janson PC, Sääf A, Lundeberg L, Tengvall-Linder   gastric cancer. Mol Cancer 2012;11:71.
               M, Norstedt G, Alenius H, Homey B, Scheynius A, Ståhle M, Pivarcsi   43.  Lu LF, Boldin MP, Chaudhry A, Lin LL, Taganov KD, Hanada T,
               A. MicroRNAs: novel regulators involved in the pathogenesis of   Yoshimura A, Baltimore D, Rudensky AY. Function of miR-146a
               psoriasis? PLoS One 2007;2:e610.                  in controlling Treg cell-mediated regulation of Th1 responses. Cell
           27.  Yi R, Poy MN, Stoffel M, Fuchs E. A skin microRNA promotes   2010;142:914-29.
               differentiation by repressing ‘stemness’. Nature 2008;452:225-9.  44.  Boldin MP, Taganov KD, Rao DS, Yang L, Zhao JL, Kalwani M,
           28.  Candi E, Cipollone R, Rivetti di Val Cervo P, Gonfloni S, Melino   Garcia-Flores Y, Luong M, Devrekanli A, Xu J, Sun G, Tay J, Linsley
               G, Knight R. p63 in epithelial development. Cell Mol Life Sci   PS, Baltimore D. miR-146a is a significant brake on autoimmunity,
               2008;65:3126-33.                                  myeloproliferation, and cancer in mice. J Exp Med 2011;208:1189-201.

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