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Sorrentino et al.                                                                                                                                                                               Role of A 2B  receptor in cancer

               and therapeutic effects of  A3 adenosine receptor agonists.  Drug   Expression of A2B adenosine receptors in human lymphocytes: their
               Discov Today 2012;17:359-66.                      role in T cell activation. J Cell Sci 1999;112:491-502.
           66.  Avni I, Garzozi HJ,  Barequet IS, Segev F, Varssano D,  Sartani G,   82.  Fredholm BB, Irenius E, Kull B, Schulte G. Comparison of the potency
               Chetrit N, Bakshi E, Zadok D, Tomkins O, Litvin G, Jacobson KA,   of adenosine as an agonist at human adenosine receptors expressed in
               Fishman S, Harpaz Z, Farbstein M, Yehuda SB, Silverman MH, Kerns   Chinese hamster ovary cells. Biochem Pharmacol 2001;61:443-8.
               WD, Bristol DR, Cohn I, Fishman P. Treatment of dry eye syndrome   83.  Eltzschig  HK, Ibla  JC, Furuta  GT, Leonard  MO, Jacobson KA,
               with orally administered CF101: data from a phase 2 clinical trial.   Enjyoji K, Robson SC, Colgan SP. Coordinated adenine nucleotide
               Ophthalmology 2010;117:1287-93.                   phosphohydrolysis and nucleoside  signaling in posthypoxic
           67.  David M, Gospodinov DK, Gheorghe N, Mateev GS, Rusinova MV,   endothelium: role of ectonucleotidases and adenosine A2B receptors.
               Hristakieva E, Solovastru LG, Patel RV, Giurcaneanu C, Hitova MC,   J Exp Med 2003;198:783-96.
               Purcaru AI, Horia B, Tsingov II, Yankova RK, Kadurina MI, Ramon   84.  Zhao P, Li XG, Yang M, Shao Q, Wang D, Liu S, Song H, Song B,
               M, Rotaru M, Simionescu O, Benea V, Demerdjieva ZV, Cosgarea   Zhang Y, Qu X. Hypoxia suppresses the production of MMP-9 by
               MR, Morariu HS, Michael Z, Cristodor P, Nica C, Silverman MH,   human monocyte-derived dendritic cells and requires activation
               Bristol DR, Harpaz Z, Farbstein M, Cohen S, Fishman P. Treatment   of adenosine receptor A2b via cAMP/PKA signaling pathway. Mol
               of plaque-type  psoriasis with oral CF101: data  from a Phase II/  Immunol 2008;45:2187-95.
               III multicenter, randomized,  controlled  trial.  J Drugs  Dermatol   85.  Feoktistov I, Ryzhov S, Zhong H, Goldstein AE, Matafonov A, Zeng
               2016;15:931-8.                                    D, Biaggioni I. Hypoxia modulates  adenosine  receptors  in human
           68.  Yang D,  Koupenova M,  McCrann DJ,  Kopeikina KJ,  Kagan HM,   endothelial  and smooth muscle cells toward an  A2B angiogenic
               Schreiber BM, Ravid K. The A2b adenosine receptor protects against   phenotype. Hypertension 2004;44:649-54.
               vascular injury. Proc Natl Acad Sci U S A 2008;105:792-6.  86.  Zhong H, Belardinelli  L, Maa  T, Zeng  D. Synergy between  A2B
           69.  Sun CX, Zhong H, Mohsenin A, Morschl E, Chunn JL, Molina JG,   adenosine receptors and hypoxia in activating human lung fibroblasts.
               Belardinelli  L, Zeng D, Blackburn MR. Role of  A2B adenosine   Am J Respir Cell Mol Biol 2005;32:2-8.
               receptor signaling in adenosine-dependent pulmonary inflammation   87.  Kong T, Westerman KA, Faigle M, Eltzschig HK, Colgan SP. HIF-
               and injury. J Clin Invest 2006;116:2173-82.       dependent induction of adenosine A2B receptor in hypoxia. FASEB J
           70.  Eckle T, Faigle M, Grenz A, Laucher S, Thompson LF, Eltzschig HK.   2006;20:2242-50.
               A2B adenosine  receptor  dampens  hypoxia-induced  vascular  leak.   88.  Xaus J, Mirabet M, Lloberas J, Soler C, Lluis C, Franco R, Celada A.
               Blood 2008;111:2024-35.                           IFN-gamma up-regulates the A2B adenosine receptor expression in
           71.  Grenz A, Osswald H, Eckle T, Yang D, Zhang H, Tran ZV, Klingel K,   macrophages: a mechanism of macrophage deactivation. J Immunol
               Ravid K, Eltzschig HK. The reno-vascular A2B adenosine receptor   1999;162:3607-14.
               protects the kidney from ischemia. PLoS Med 2008;5:e137.  89.  Németh ZH, Leibovich  SJ, Deitch EA,  Vizi ES, Szabó C, Hasko
           72.  Ryzhov S, Novitskiy SV, Zaynagetdinov R, Goldstein AE, Carbone   G. cDNA microarray  analysis  reveals  a nuclear  factor-kappaB-
               DP, Biaggioni I, Dikov MM, Feoktistov I. Host  A(2B) adenosine   independent  regulation of macrophage function  by adenosine.  J
               receptors promote carcinoma growth. Neoplasia 2008;10:987-95.  Pharmacol Exp Ther 2003;306:1042-9.
           73.  Cagnina RE, Ramos SI, Marshall MA, Wang G, Frazier CR, Linden   90.  St Hilaire C, Koupenova M, Carroll SH, Smith BD, Ravid K.
               J.  Adenosine  A2B receptors  are  highly  expressed  on murine  type   TNF-alpha upregulates the  A2B adenosine receptor gene: the
               II alveolar epithelial  cells.  Am J  Physiol  Lung Cell  Mol  Physiol   role of NAD(P)H oxidase 4.  Biochem Biophys Res Commun
               2009;297:L467-74.                                 2008;375:292-6.
           74.  Yang D, Zhang Y, Nguyen HG, Koupenova M, Chauhan AK, Makitalo   91.  Nguyen DK, Montesinos MC, Williams AJ, Kelly M, Cronstein BN.
               M, Jones MR, St Hilaire C, Seldin DC, Toselli P, Lamperti E, Schreiber   Th1 cytokines regulate  adenosine  receptors and their  downstream
               BM, Gavras H, Wagner DD, Ravid K. The A2B adenosine receptor   signaling elements  in human microvascular endothelial  cells.  J
               protects against inflammation and excessive vascular adhesion. J Clin   Immunol 2003;171:3991-8.
               Invest 2006;116:1913-23.                       92.  Schingnitz U, Hartmann K, Macmanus CF, Eckle  T, Zug S,
           75.  Casadó V, Casillas T, Mallol J, Canela EI, Lluis C, Franco R. The   Colgan SP, Eltzschig HK. Signaling through the  A2B adenosine
               adenosine receptors present on the plasma membrane of chromaffin   receptor dampens endotoxin-induced acute lung injury. J Immunol
               cells are of the A2b subtype. J Neurochem 1992;59:425-31.  2010;184:5271-9.
           76.  Peakman  MC,  Hill  SJ.  Adenosine  A2B-receptor-mediated  cyclic   93.  Kolachala VL, Wang L, Obertone TS, Prasad M, Yan Y, Dalmasso
               AMP accumulation in primary rat astrocytes.  Br J Pharmacol   G,  Gewirtz  AT, Merlin D,  Sitaraman SV.  Adenosine 2B receptor
               1994;111:191-8.                                   expression is post-transcriptionally regulated by microRNA. J Biol
           77.  Corset  V, Nguyen-Ba-Charvet  KT, Forcet C, Moyse E, Chédotal   Chem 2010;285:18184-90.
               A, Mehlen  P. Netrin-1-mediated  axon  outgrowth  and  cAMP   94.  Nakatsukasa H, Tsukimoto M, Harada H, Kojima S. Adenosine A2B
               production requires interaction with adenosine A2b receptor. Nature   receptor  antagonist  suppresses differentiation  to regulatory  T cells
               2000;407:747-50.                                  without suppressing activation  of  T cells.  Biochem  Biophys Res
           78.  Nishida K, Dohi Y, Yamanaka Y, Miyata A, Tsukamoto K, Yabu M,   Commun 2011;409:114-9.
               Ohishi A, Nagasawa K. Expression of adenosine A2b receptor in rat   95.  Warabi M, Kitagawa M, Hirokawa K. Loss of MHC class II
               type II and III taste cells. Histochem Cell Biol 2014;141:499-506.  expression  is  associated  with  a  decrease  of  tumor-infiltrating  T
           79.  Hua X, Kovarova M, Chason KD, Nguyen M, Koller BH, Tilley SL.   cells and an increase of metastatic potential of colorectal cancer:
               Enhanced mast cell activation in mice deficient in the A2b adenosine   immunohistological and histopathological analyses as compared
               receptor. J Exp Med 2007;204:117-28.              with normal colonic mucosa and adenomas.  Pathol Res Pract
           80.  Novitskiy SV, Ryzhov S, Zaynagetdinov R, Goldstein AE, Huang Y,   2000;196:807-15.
               Tikhomirov OY, Blackburn MR, Biaggioni I, Carbone DP, Feoktistov   96.  Shi B, Vinyals A, Alia P, Broceno C, Chen F, Adrover M, Gelpi C,
               I, Dikov MM.  Adenosine  receptors  in regulation  of dendritic  cell   Price JE, Fabra A. Differential expression of MHC class II molecules
               differentiation and function. Blood 2008;112:1822-31.  in highly metastatic breast cancer cells is mediated by the regulation
           81.  Mirabet M, Herrera C, Cordero OJ, Mallol J, Lluis C, Franco R.   of  the  CIITA  transcription  Implication  of  CIITA  in  tumor  and
                           Journal of Cancer Metastasis and Treatment ¦ Volume 3 ¦ July 17, 2017          137
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