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Figure 63. Microbial transformation of melengestrol acetate (352) with Glomerella fusarioides,and Rhizopus stolonifer.
Figure 64. Microbial transformation of medrysone (357) with Cunninghamella blakesleeana.
Figure 65. Biotransformation of (E)-guggulsterone (365) with Rhizopus stolonifer.
Biotransformation of physalin H (373)
Rhizopus stolonifer-catalyzed the transformation of physalin H (373) and yielded the new derivative, 6, 7-
dehydrophysalin H (374) (2.10%) [Figure 67], while structural transformation with Cunninghamella
[87]
elegans afforded a new compound, 6-deoxyphysalin H (375) (4.10%), along with the known metabolite,
