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Hwang et al. Plast Aesthet Res 2017;4:9-12 Plastic and
DOI: 10.20517/2347-9264.2016.78
Aesthetic Research

www.parjournal.net
Case Report Open Access

In vivo degradation of poly L-lactic D-lactic

acid and tri-methylene carbonate sheets in

orbital reconstruction

Kun Hwang , Hyung Mook Kim 2
1
1 Department of Plastic Surgery, Inha University School of Medicine, Incheon 22332, South Korea.
2 Department of Plastic Surgery, Inha University Hospital, Incheon 22332, South Korea.
Correspondence to: Dr. Kun Hwang, Department of Plastic Surgery, Inha University School of Medicine, 27 Inhang-ro, Jung-gu, Incheon 22332,
South Korea. E-mail: jokerhg@inha.ac.kr
How to cite this article: Hwang K, Kim HM. In vivo degradation of poly L-lactic D-lactic acid and tri-methylene carbonate sheets in orbital
reconstruction. Plast Aesthet Res 2017;4:9-12.

Dr. Kun Hwang is currently a Fellowship Professor, Department of Plastic Surgery, Inha University School of Medicine
and Inha University Hospital. More information could be found at: http://orcid.org/0000-0002-1994-2538.

ABSTRACT

Article history: This study was conducted to evaluate changes in the composition of a poly-L-lactic D-lactic
Received: 19-09-2016 acid and trimethylene carbonate (PLDLA-TMC) sheet after insertion into the human body.
Accepted: 16-01-2017 A 35-year-old woman had an orbital fracture that was reconstructed using a PLDLA-TMC
Published: 19-01-2017 sheet. During iliac bone grafting for enophthalmos 190 days after the insertion, the sheet
was removed and analyzed using gel permeation chromatography and Fourier transform
infrared spectroscopy. The weight average molecular weight decreased (from 151,000 Da
Key words: to 10,000 Da), as did the number average molecular weight (from 15,600 Da to 255 Da).
Poly(lacticide-co-trimethylene An amide functional group peaks at 1,655.43 cm (1,670-1,640 cm ) and its stretch band at
-1
-1
carbonate), 1,541.26 cm (1,640-1,550 cm ) newly appeared due to serum or tissue fluid incorporation.
-1
-1
spectroscopy, PLDLA-TMC is expected to exhibit favorable degradation properties.
fourier transform infrared,
chromatography,
gel,
orbit,
orbital fractures

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