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Fok et al. Skin temperature of laser for Nevus of Ota

results. This will make the delivery of skin heat transfer Board at Chang Gung Memorial Hospital.
easier and more precise.
REFERENCES
In our study, real-time monitoring with photothermal
images and the prediction of temperature was reliable 1. Hidano A, Kajima H, Ikeda S, Mizutani H, Miyasato H, Niimura M.
when using the thermal wave equation. We were able Natural history of nevus of Ota. Arch Dermatol 1967;95:l87-95.
to clearly observe how the temperature distribution 2. Font RL, Reynolds AM Jr., Zimmerman LE. Diffuse malignant
of heat transfer and the features of the thermal wave melanoma of the iris in the nevus of Ota. Arch Ophthalmol
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study also showed different predictions of QSRL contalateral cerebral melanoma. Arch Ophthalmol 1977;95:1820-4.
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showed that the effective energy density of lasers Anderson RR. Treatment of tattoos by Q-switched ruby laser. A dose-
should be lower than 8 J/cm based on the thermal response study. Arch Dermatol 1990;126:893-9.
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Nevus of Ota patients with definitive treatment, exact Microsurgical treatment of meningeal malignant melanoma
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Melanoma Res 2013;23:502-4.
patient and careful consideration of age, skin type, and 8. Tregnago AC, Furlan MV, Bezerra SM, Porto GC, Mendes GG,
area in-line for treatment all must be administered for a Henklain JV, Pinto CA, Kowalski LP, de Carvalho GB, Costa FD.
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in association with ipsilateral nevus of Ota: report of a case and review
In conclusion, laser illumination requires an extremely of the literature. Head Neck 2015;37:E49-55.
short time and its heat flux is extremely high in cutaneous 9. Rastogi S, Chaudhari P. Pigment reduction in nevus of Ota following
leech therapy. J Ayurveda Integr Med 2014;5:125-8.
laser surgery. For prevention of complications, it is 10. Geronemus RG. Q-switched ruby laser therapy of neuus of Ota. Arch
necessary to take the thermal wave effect into account. Dermatol 1992;128:1618-22.
Real-time photothermal imaging and prediction of 11. Taylor CR, Flotte TJ, Gange RW, Anderson RR. Treatment of nevus of
temperature response on the lesion site derived from Ota by Q-switched ruby laser. J Am Acad Dermatol 1994;30:743-51.
this study is helpful for determining the energy density 12. Chang CJ, Nelson JS. Q-switched ruby laser treatment of
for laser treatment of Nevus of Ota patients. The mucocutaneous melanosis associated with peutz-jeghers syndrome.
Ann Plast Surg 1996;36:394-7.
effective energy density of lasers should be lower than 13. Chang CJ, Kou CS. Comparing the effectiveness of Q-switched Ruby
8 J/cm to avoid complications. This study can serve laser treatment with that of Q-switched Nd:YAG laser for oculodermal
2
as a precedent for increased and improved safety of melanosis (Nevus of Ota). Br J Plast Surg 2011;64:339-45.
laser surgery patients and lay groundwork for research 14. Felton SJ, Al-Niaimi F, Ferguson JE, Madan V. Our perspective of the
of other laser treatments. treatment of naevus of Ota with 1,064-, 755- and 532-nm wavelength
lasers. Lasers Med Sci 2014;29:1745-9.
Financial support and sponsorship 15. Zong W, Lin T. A retrospective study on laser treatment of nevus of
Ota in Chinese children--a seven-year follow-up. J Cosmet Laser Ther
This project was supported by research grants awarded from 2014;16:156-60.
the National Science Council in Taiwan (NMRPG34661:94- 16. Wen X, Li Y, Jiang X. A randomized, split-face clinical trial of
2213-E-182A-002, NMRPG34662: 95-2221-E-182A-003, Q-switched alexandrite laser versus Q-switched Nd:YAG laser in the
treatment of bilateral nevus of Ota. J Cosmet Laser Ther 2015;18:12-5.
NMRPG376311:97-2221-E-182A-001-MY3) and Chang 17. Chesnut C, Diehl J, Lask G. Treatment of nevus of ota with a
Gung Memorial Hospital (CMRP606, CMRP 812, picosecond 755-nm alexandrite laser. Dermatol Surg 2015;41:508-10.
CMRPG3B0301, CMRPG3B0302, CMRPG3E0581). 18. Yates B, Que SK, D’Souza L, Suchecki J, Finch JJ. Laser treatment of
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Conflicts of interest 19. Sober AJ. The Year Book of Dermatology. Chicago: Mosby; 1997.
There are no conflicts of interest. p. 383-4.
20. Apfelberg DB, Maser MR, Lash H, Rivers J. The argon laser for
cutaneou lesions. JAMA 1981;245:2073-5.
Patient consent 21. Apfelberg DB. Argon and Q-switched yttrium-aluminum-garnet laser
All patients gave informed consent. treatment of nevus of Ota. Ann Plast Surg 1995;35:150-3.
22. Chang CJ, Nelson JS, Achauer BM. Q-switiched ruby laser of
Ethics approval oculodermal melanosis (nevus of Ota). Plast Reconstr Surg
1996;98:784-90.
The study was approved by the Institutional Review 23. Lawrence SB, Michael RT. Laser tissue welding: a comprehensive
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