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Jun. Plast Aesthet Res 2017;4:104-5 Plastic and
DOI: 10.20517/2347-9264.2017.18
Aesthetic Research

www.parjournal.net
Commentary Open Access
Comment on “Multipotency and secretome:

the mechanisms behind the regenerative

potential of adipose-derived stem cells”

Young-Joon Jun
Department of Plastic and Reconstructive Surgery, The Catholic University of Korea, Bucheon 14647, South Korea.
Correspondence to: Dr. Young-Joon Jun, Department of Plastic and Reconstructive Surgery, The Catholic University of Korea, 327 Sosa-ro,
Wonmi-gu, Bucheon 14647, South Korea. E-mail: joony@catholic.ac.kr
How to cite this article: Jun YJ. Comment on “Multipotency and secretome: the mechanisms behind the regenerative potential of adipose-derived stem
cells”. Plast Aesthet Res 2017;4:104-5.

Article history: Received: 28-02-2017 Accepted: 07-04-2017 Published: 27-06-2017

Dr. Young-Joon Jun is the Chief Professor of Plastic and Reconstructive Surgery at Catholic University of Korea.
He is currently the Head of Training and Education at Bucheon St. Mary’s Hospital. He is also the Director of Public
Relation Committee of the Korean Society of the Plastic and Reconstructive Surgery, the Director of Insurance Affairs
Committee of the Korean Wound Management Society, and the Director of Information Technology Committee of the
Korean Society for Aesthetic Plastic Surgery.

"Orgun D, Mizuno H. Multipotency and secretome: embryonicorgan systems. They play an important role in
the mechanisms behind the regenerative potential regeneration of organs and tissues throughout life. There
of adipose-derived stem cells. Plast Aesthet Res are two basic types of stem cells: embryonic stem cells
2017;4:32-40.” derived from blasto-cytes, and adult stem cells obtained
from fully developed adult tissue or placenta. Embryonic
The application of stem cells technology to the stem cells proliferate with ease due to great self-replicating
intractable disease has emerged in the 21st century. ability of their undifferentiated state. However, applying
It has been applied to almost all areas of medicine, this knowledge raises ethical problems. Therefore,
including cardiovascular, nervoulogic, hematologic, studies on adult stem cells are in progress.
genetic, liver, endocrine and musculoskeletal
diseases. In particular, stem cell mediated tissue Bone marrow-derived stem cells are one of better-
regeneration has opened treatment options for characterized adult stem cells. [1,2] However, harvesting
previously-considered intractable diseases, with no these bone marrow remains a challenge, and their
other treatment alternatives. isolation and yield ability is relatively low. For sufficient
amounts of clinical use, multiple samples are required.
Stem cells have the ability of self-replicating and Therefore, researchers have begun to explore new
[3]
differentiate into cells that make up various post- alternative sources of stem cells. Zuk et al. reported
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