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Barel et al. Plast Aesthet Res 2016;3:368-74                                       Plastic and
           DOI: 10.20517/2347-9264.2015.81
                                                                                  Aesthetic Research

                                                                                               www.parjournal.net
             Original Article                                                                   Open Access

           Non-invasive focused ultrasound for

           abdominal circumference reduction: does it

           really work?



           Eric Barel , Abraham Amir , Asaf Olshinka , Dean Ad-El 1
                                   1
                    1,2
                                                 1
           1 Department of Plastic and Reconstructive Surgery, Rabin Medical Center, Beilinson Hospital (affiliated with Sackler Faculty of Medicine, Tel Aviv
           University), Petach Tikva 49100, Israel.
           2 Post-Barriatric Plastic Surgery Clinic, Rabin Medical Center, Beilinson Hospital (affiliated with Sackler Faculty of Medicine, Tel Aviv University), Petach
           Tikva 49100, Israel.
           Correspondence to: Dr. Eric Barel, Department of Plastic and Reconstructive Surgery, Rabin Medical Center, Beilinson Hospital (affiliated with
           Sackler Faculty of Medicine, Tel Aviv University), Petach Tikva 49100, Israel. E-mail: eric@drbarel.com
           How to cite this article: Barel E, Amir A, Olshinka A, Ad-El D. Non-invasive focused ultrasound for abdominal circumference reduction: does it
           really work? Plast Aesthet Res 2016;3:368-74.
                                         ABSTRACT
            Article history:              Aim: Non-invasive body contouring is a promising modality. However, due to a lack of good
            Received: 29-07-2015          evidence-based data, the mechanism by which contouring occurs remains unclear. The purpose
            Accepted: 27-10-2016          of this study was to evaluate the effect of treatment with the Contour I™ ultrasound system
                                                  ®
            Published: 14-12-2016         (Ultrashape , Syneron , Israel) on abdominal circumference and to compare 2 power levels
                                                          ®
                                          for efficacy and safety. Methods: A prospective, self-controlled double-blind design was used.
            Key words:                    Thirty-six women, aged 30-45 years, were randomized to receive treatment with the Contour I
            Body contouring,              at high or low acoustic outputs in 3 successive sessions, 1 month apart. Safety was evaluated by
            ultrasound,                   adverse events, local skin reaction, and pain. Efficacy was evaluated by the change in abdominal
            fat cell disruption,          circumference relative to baseline and to the untreated thigh area (internal control). Patients were
            liposuction,                  followed for 28 days after the last treatment session. Results: At 1 month after the first session,
            non-invasive                  the mean reductions in abdominal circumference measured 1.65 cm (P < 0.001) and 0.87 cm
                                          (P < 0.019) in the high and low-power groups, respectively. At 1 month after the last session,
                                          the cumulative reductions in circumference were 2.56 cm (P < 0.001) and 1.49 cm (P < 0.012),
                                          respectively. There was no change in the internal-control circumference throughout treatment.
                                          There  were  no  treatment-induced  severe  adverse  events.  Conclusion: Multiple successive
                                          treatments of the abdominal area with the Contour I lead to a significant progressive reduction in
                                          circumference. The magnitude of the reduction is directly correlated to the acoustic power output
                                          which suggests that the technology itself is the main cause for the contouring effect.


           INTRODUCTION                                       non-invasive alternatives to traditional liposuction given
                                                              the risk of complications [1-5]  and prolonged downtime.
                                                                                                            [6]
           Body contouring is one of the most popular procedures   Multiple modalities have been developed including the
           in aesthetic medicine. There is a growing demand for   use of laser and radio-frequency assisted liposuction,

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