Page 270 - Read Online
P. 270

determined to affect wound complications after breast reduction without increased detriment on other
                  major complications when compared to the non-obese. Obesity should be a considered with other
                  preoperative comorbidities, rather than an independent contraindication to surgery. Breast reduction
                  appears to be safe in the obese patient who is otherwise healthy.
                  Key words:

                  Obesity; breast reduction; reduction mammoplasty;  National Surgical Quality Improvement
                  Program; propensity score




            INTRODUCTION                                      on multivariable analysis. However, no study to date has
                                                              harvested the statistical power of the NSQIP dataset with
            Breast reduction surgery, or reduction mammaplasty,   the  use  of propensity  score  matching  to evaluate the
            is a commonly performed procedure for the treatment   effect of obesity as an independent risk factor on breast
            of symptomatic macromastia.  Over  101,000  breast   reduction outcomes. Multivariable analysis attempts
            reductions were performed in 2014.  Patients seek relief   to control for heterogeneity  between patient cohorts
                                          [1]
            from back and neck pain, intertriginous rashes, shoulder   via  advanced statistical  techniques.  Patient  matching,
            grooving,  ill-fitting  clothing, and dissatisfaction with   however, eliminates  heterogeneity  between  patient
            breast appearance. Breast reduction has been shown to   cohorts by 1:1 matching each experimental group patient
            improve physical, psychosocial, and sexual well-being.    with a control group patient with similar characteristics.
                                                          [2]
            Patients experience enhanced quality of life  and are   The goal of this study is to isolate the effect of obesity on
                                                  [3]
            highly satisfied with the procedure. [4,5]        breast reduction outcomes using 1:1 patient matching.
            The incidence of postoperative complications in reduction   METHODS
            mammaplasty is relatively low, approximately  6%.
                                                          [6]
            Problems range from minor wound complications and   Data acquisition
            infections to significant bleeding and thromboembolic   Patients  undergoing  primary  reduction mammaplasty
            events. Thorough preoperative assessment is imperative   were identified from the 2005-2013 ACS-NSQIP registry.
            to patient safety and avoiding poor surgical outcomes.
                                                              Methods for data acquisition involved trained research
                                                              nurses from participating institutions in the United
            Many women suffering from symptomatic macromastia   States who collected data through systemic sampling of
            are obese. Given the increasing number of obese patients   surgical procedures, as previously described.  A total
                                                                                                    [18]
            in the general population, the role of body mass index
            (BMI) as a preoperative assessment  factor remains  of   of 240  variables were collected  for each case. Further
            great interest to the surgical community. Obese patients   information can be accessed via the ACS-NSQIP website
            are more likely to have medical comorbidities, including   at http://www.acsnsqip.org/.  Data are depersonalized
            hypertension,  diabetes,  chronic respiratory disease   and Health Insurance Portability and Accountability Act
            and obstructive sleep apnea. They are 35% more likely   compliant.
            to have an emergency department visit or hospital
                                                    [7]
            admission  30 days after outpatient  surgery.  Many   The  NSQIP  registry  was  queried  using  Current
            surgeons require obese patients to lose weight prior to   Procedural Terminology code 19318 to identify patients
            undergoing  surgery, and certain insurance carriers use   who had undergone reduction mammaplasty. Patients
            higher weights  as refusal criteria for coverage.  The   were then characterized according to the World Health
                                                     [8]
            role of obesity in postoperative complications following   Organization (WHO) classification of obesity: non-obese
                                                                            2
                                                                                                           2
            reduction mammaplasty is inconsistently defined in the   (BMI < 30 kg/m ), class I obesity (BMI 30-34.9 kg/m ),
                                                                                           2
            literature. Some studies associate obesity with increased   class II obesity (BMI 35-39.9 kg/m ), or class III (BMI ≥
                                                                     2
            postoperative complications, [9-13]  whereas others find no   40  kg/m ).  Inclusion  criteria  included  primary  bilateral
            statistically significant correlation. [14-17]    breast reductions.
            In 2014,  Nelson  et al.  studied obesity and  reduction   Outcome variables
                               [6]
            mammaplasty using the 2005-2011 American College of   Primary outcomes of interest were analyzed through
            Surgeons - National Surgical Quality Improvement Program   several pre-defined NSQIP  variables, including patient
            (ACS-NSQIP) datasets. NSQIP is a nationally-validated,   demographics and comorbidities, as well as early surgical
            risk-adjusted surgical outcomes database to measure   complications, defined as adverse events occurring within
            and improve the  quality  of surgical care.  The  authors   30 days after surgery. Demographics included race and
            reported an increased rate of overall complications in the   age. Comorbidities included diabetes (further classified
            early 30-day postoperative period among obese patients   into insulin dependent and non-insulin dependent),
            260                                                                Plast Aesthet Res || Volume 3 || July 28, 2016
   265   266   267   268   269   270   271   272   273   274   275