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Wang et al. Cytology of cerebrospinal and superficial siderosis

MRI. We were unable to identify the exact source of showed that reliable changes of the head imaging.
the bleeding, however, bleeding was present in the Combined with the patient’s clinical manifestations,
subarachnoid space. the diagnosis of SSCNS was obtained. T2-weighted
MRI used together with the CCSF is strongly
T2-weighted MR imaging typically reports hypointensity recommended in differential diagnosis of SSCNS.
along the surface of cerebellum and brainstem,
corresponding to the deposition of hemosiderin. DECLARATIONS
Cerebellar atrophy is also commonly associated
with SSCNS. In our case, T2-weighted images Authors’ contributions
[7]
showed a rim of hypointensity around the cerebellum, Conception, diagnosis and design: C. Wang
brainstem, and Sylvian fissure, which helped us to Manuscript preparation: J.X. Diao
diagnose this patient with SSCNS. In recent years, Pathology diagnosis: S.M. Li
RBCs have been observed in CSF studies with Manuscript revision: C. Wang
SSCNS. The presence of RBCs in the CSF is the Final approval of manuscript: C. Wang
defining feature of SSCNS. A non-traumatic lumbar
puncture was performed in our patient, the color was Financial support and sponsorship
pale red. CSF was full of characteristics following None.
analysis and cytology. It showed a large number of
RBCs and obvious neutrophilic response. There were Conflicts of interest
erythrocyte phagocytes and hemosiderin phagocytic There are no conflicts of interest.
cells measure in the CCSF. Seven days later, we
were able to see bilirubin phagocytes. All the above Patient consent
types of phagocytic cells suggested that the cerebral Patient consent was obtained from the patient.
hemorrhage had not stopped or might be a sign of
rebleeding. This kind of performance was consistent Ethics approval
[8]
with its pathogenesis and pathophysiology. From There is no ethics issue in this paper.
what has been discussed above, CCSF can prompt
the pathogenesis of the SSCNS, it was identified a REFERENCES
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