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Chen                                                                                                                                                                                  MAGL in neurodegenerative diseases

           REFERENCES                                            neurodegenerative diseases. Rev Neurosci 2016;27:93-100.
                                                              10.  Djordjevic  J,  Sabbir  MG, Albensi  BC. Traumatic  brain  injury  as  a
           1.   Gaoni Y, Mechoulam R. Isolation, structure and partial synthesis of an   risk factor for Alzheimer’s disease: is inflammatory signaling a key
               active constituent of hashish. J Am Chem Soc 1964;86:1646-7.  player? Curr Alzheimer Res 2016;13:730-8.
           2.   Kano M, Ohno-Shosaku  T, Hashimotodani  Y, Uchigashima  M,   11.  Zhang J, Hu M, Teng Z, Tang YP, Chen C. Synaptic and cognitive
               Watanabe  M.  Endocannabinoid-mediated  control  of  synaptic   improvements  by  inhibition  of  2-AG  metabolism  are  through
               transmission. Physiol Rev 2009;89:309-80.         upregulation of microRNA-188-3p in a mouse model of Alzheimer’s
                                                                 disease. J Neurosci 2014;34:14919-33.
           3.   Castillo PE, Younts TJ, Chávez AE, Hashimotodani Y. Endocannabinoid   12.  Chen R, Zhang J, Wu Y, Wang D, Feng G, Tang YP, Teng Z, Chen
               signaling and synaptic function. Neuron 2012;76:70-81.  C.  Monoacylglycerol  lipase  is  a  therapeutic  target  for Alzheimer’s
           4.   Xu  JY,  Chen  C.  Endocannabinoids  in  synaptic  plasticity  and   disease. Cell Rep 2012;2:1329-39.
               neuroprotection. Neuroscientist 2015;21:152-68.  13.  Nomura  DK,  Morrison  BE,  Blankman  JL,  Long  JZ,  Kinsey  SG,
           5.   Zhang  J,  Chen  C.  Endocannabinoid  2-arachidonoylglycerol  protects   Marcondes MC, Ward AM, Hahn YK, Lichtman AH, Conti B, Cravatt
               neurons by limiting COX-2 elevation. J Biol Chem 2008;283:22601-11.  BF. Endocannabinoid hydrolysis generates brain prostaglandins that
           6.   Blankman JL, Simon GM, Cravatt BF. A comprehensive profile of brain   promote neuroinflammation. Science 2011;334:809-13.
               enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol.   14.  Piro  JR,  Benjamin  DI,  Duerr  JM,  Pi  Y,  Gonzales  C,  Wood
               Chem Biol 2007;14:1347-56.                        KM,  Schwartz  JW,  Nomura  DK,  Samad  TA.  A  dysregulated
           7.   Panikashvili  D,  Simeonidou  C,  Ben-Shabat  S,  Hanus  L,  Breuer A,   endocannabinoid-eicosanoid  network  supports  pathogenesis  in  a
               Mechoulam  R, Shohami E. An endogenous cannabinoid  (2-AG) is   mouse model of Alzheimer’s disease. Cell Rep 2012;1:617-23.
               neuroprotective after brain injury. Nature 2001;413:527-31.  15.  O’Sullivan  SE.  Cannabinoids  go  nuclear:  evidence  for  activation
           8.   Zhang  J,  Teng  Z,  Song  Y,  Hu  M,  Chen  C.  Inhibition  of   of  peroxisome  proliferator-activated  receptors.  Br J Pharmacol
               monoacylglycerol lipase prevents chronic traumatic encephalopathy-  2007;152:576-82.
               like neuropathology in a mouse model of repetitive mild closed head   16.  Du H, Chen X, Zhang J, Chen C. Inhibition of COX-2 expression by
               injury. J Cereb Blood Flow Metab 2015;35:443-53.  endocannabinoid 2-arachidonoylglycerol is mediated via PPAR-γ. Br
           9.   Gupta  R,  Sen  N.  Traumatic  brain  injury:  a  risk  factor  for   J Pharmacol 2011;163:1533-49.



















































            270                                                                 Neuroimmunology and Neuroinflammation ¦ Volume 3 ¦ December 15, 2016
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