Page 25 - Read Online
P. 25
Figure 5: Magnetic resonance angiography showing patent basilar tip and
posterior cerebral arteries. (a) Anterior view; (b) lateral view right side
presentation. Long‑term anticoagulant therapy is the
current treatment strategy suggested for AOP occlusion. [7]
Figure 4: Magnetic resonance imaging brain T2‑weighted sequences showing In comparison to ischemic lesions of other
V‑shaped hyper‑intense signal areas in the pial surface of the midbrain
adjacent to the interpeduncular fossa without any abnormal signs in this region cortical‑subcortical structures, thalamic stroke has a
lower mortality rate and a better prognosis as far as the
[2]
impairment (58%), confusion (53%), and coma (42%). recovery of motor deficits is concerned. On the contrary,
Vertical gaze palsy is due to the disruption of the cortical the neuropsychological deficits in terms of memory,
input that traverses the thalamus to reach the rostral cognition, emotional response and behavior tend to
interstitial medial longitudinal fasciculus. Memory persist, and interfere with the social and professional life
[3]
impairment, confusion, and coma classically seen in of the patient.
bilateral thalamic infarction, often called together as
“thalamic dementia” is explained by the involvement In conclusion, occlusion of the AOP is a rare cause of coma
of the reticular activating system and the disrupted in elderly patients. Diffusion‑weighted MRI is the imaging
[4]
connections between the thalamus and the cortex. modality of choice for early diagnosis. Early diagnosis of
Thalamic dementia does not develop in case of unilateral AOP occlusion may lead to favorable outcomes.
lesions.
Financial support and sponsorship
These patients must be differentiated from those with Nil.
“top of the basilar artery” syndrome and deep cerebral
venous thrombosis (DCVT). [5,6] “Top of the basilar artery” Conflicts of interest
syndrome tends to involve the superior cerebellar artery There are no conflicts of interest.
and posterior cerebral artery territories. MRI showing
patent basilar tip and posterior cerebral arteries exclude REFERENCES
this diagnosis in our patient. MRI pattern does not confine
to a typical arterial territory in DCVT. 1. Chang YM, Fan YK. Artery of percheron occlusion in an elderly male: a
case report. J Clin Med Res 2015;7:126‑8.
2. Lamot U, Ribaric I, Popovic KS. Artery of Percheron infarction: review
Percheron described four normal variations of the of literature with a case report. Radiol Oncol 2015;49:141‑6.
neurovascular anatomy of the thalamus and the 3. Monet P, Monet P, Garcia PY, Saliou G, Spagnolo S, Desblache J,
Franc J, Vallée JN, Deramond H, Lehmann P. Bithalamic infarct: is
midbrain. The medial part of the thalamus is supplied there an evocative aspect? Radioclinical study. Rev Neurol (Paris)
[2]
from the posterior circulation via the perforating thalamic 2009;165:178‑84.
arteries, which are also known as the paramedian 4. Lazzaro NA, Wright B, Castillo M, Fischbein NJ, Glastonbury CM,
Hildenbrand PG, Wiggins RH, Quigley EP, Osborn AG. Artery of
arteries. Occlusion of AOP causes a bilateral paramedian percheron infarction: imaging patterns and clinical spectrum. AJNR Am
[2]
thalamic and rostral midbrain infarction. Most of the J Neuroradiol 2010;31:1283‑9.
AOP infarction is due to small vessel occlusion or cardiac 5. Rodriguez EG, Lee JA. Bilateral thalamic infarcts due to occlusion of
the Artery of Percheron and discussion of the differential diagnosis of
embolism. [5] bilateral thalamic lesions. J Radiol Case Rep 2013;7:7‑14.
6. Kostanian V, Cramer SC. Artery of Percheron thrombolysis. AJNR Am
Successful tissue plasminogen activator therapy for J Neuroradiol 2007;28:870‑1.
[7]
AOP occlusion is reported in literature, but our patient 7. Li X, Agarwal N, Hansberry DR, Prestigiacomo CJ, Gandhi CD.
Contemporary therapeutic strategies for occlusion of the artery of
was outside the treatment time window on the initial Percheron: a review of the literature. J Neurointerv Surg 2015;7:95‑8.
16 Neuroimmunol Neuroinfammation | Volume 3 | Issue 1 | January 20, 2016