Page 92 - Read Online

19. Aoki T, Kataoka H, Morimoto M, Nozaki K, Hashimoto N. markers in intracranial aneurysm using genome‑wide association
Macrophage‑derived matrix metalloproteinase‑2 and ‑9 data from two different populations. PLoS One 2013;8:e57022.
promote the progression of cerebral aneurysms in rats. Stroke 35. de Rooij NK, Linn FH, van der Plas JA, Algra A, Rinkel GJ. Incidence
2007;38:162‑9. of subarachnoid haemorrhage: a systematic review with emphasis on
20. Frösen J, Piippo A, Paetau A, Kangasniemi M, Niemelä M, region, age, gender and time trends. J Neurol Neurosurg Psychiatry
Hernesniemi J, Jaaskelainen J. Remodeling of saccular cerebral 2007;78:1365‑72.
artery aneurysm wall is associated with rupture: histological analysis 36. Kurki MI, Gaál EI, Kettunen J, Lappalainen T, Menelaou A,
of 24 unruptured and 42 ruptured cases. Stroke 2004;35:2287‑93. Anttila V, van ‘t Hof FN, von Und Zu Fraunberg M, Helisalmi S,
21. Kanematsu Y, Kanematsu M, Kurihara C, Tada Y, Tsou TL, van Hiltunen M, Lehto H, Laakso A, Kivisaari R, Koivisto T,
Rooijen N, Lawton MT, Young WL, Liang EI, Nuki Y, Hashimoto T. Ronkainen A, Rinne J, Kiemeney LA, Vermeulen SH, Kaunisto MA,
Critical roles of macrophages in the formation of intracranial Eriksson JG, Aromaa A, Perola M, Lehtimaki T, Raitakari OT,
aneurysm. Stroke 2011;42:173‑8. Salomaa V, Gunel M, Dermitzakis ET, Ruigrok YM, Rinkel GJ,
22. Hasan D, Chalouhi N, Jabbour P, Hashimoto T. Macrophage Niemela M, Hernesniemi J, Ripatti S, de Bakker PI, Palotie A,
imbalance (M1 vs. M2) and upregulation of mast cells in wall Jaaskelainen JE. High risk population isolate reveals low frequency
of ruptured human cerebral aneurysms: preliminary results. variants predisposing to intracranial aneurysms. PLoS Genet
J Neuroinflammation 2012;9:222. 2014;10:e1004134.
23. Chalouhi N, Points L, Pierce GL, Ballas Z, Jabbour P, Hasan D. 37. Zhang Y, Lang Q, Li J, Xie F, Wan B, Yu L. Identification and
Localized increase of chemokines in the lumen of human cerebral characterization of human LYPD6, a new member of the Ly‑6
aneurysms. Stroke 2013;44:2594‑7. superfamily. Mol Biol Rep 2010;37:2055‑62.
24. Aoki T, Kataoka H, Ishibashi R, Nozaki K, Egashira K, Hashimoto N. 38. Nigro P, Abe J, Berk BC. Flow shear stress and atherosclerosis: a
Impact of monocyte chemoattractant protein‑1 deficiency on matter of site specificity. Antioxid Redox Signal 2011;15:1405‑14.
cerebral aneurysm formation. Stroke 2009;40:942‑51. 39. Murakami K, Tanaka M, Usui T, Kawabata D, Shiomi A,
25. Aoki T, Fukuda M, Nishimura M, Nozaki K, Narumiya S. Critical role Iguchi‑Hashimoto M, Shimizu M, Yukawa N, Yoshifuji H, Nojima T,
of TNF‑alpha‑TNFR1 signaling in intracranial aneurysm formation. Ohmura K, Fujii T, Umehara H, Mimori T. Follistatin‑related protein/
Acta Neuropathol Commun 2014;2:34. follistatin‑like 1 evokes an innate immune response via CD14 and
26. Ali MS, Starke RM, Jabbour PM, Tjoumakaris SI, Gonzalez LF, toll‑like receptor 4. FEBS Lett 2012;586:319‑24.
Rosenwasser RH, Owens GK, Koch WJ, Greig NH, Dumont AS. 40. Liu L, Aerbajinai W, Ahmed SM, Rodgers GP, Angers S, Parent CA.
TNF‑α induces phenotypic modulation in cerebral vascular smooth Radil controls neutrophil adhesion and motility through ß2‑integrin
muscle cells: implications for cerebral aneurysm pathology. J Cereb activation. Mol Biol Cell 2012;23:4751‑65.
Blood Flow Metab 2013;33:1564‑73. 41. Stefansson B, Ohama T, Daugherty AE, Brautigan DL. Protein
27. Aoki T, Kataoka H, Shimamura M, Nakagami H, Wakayama K, phosphatase 6 regulatory subunits composed of ankyrin repeat
Moriwaki T, Ishibashi R, Nozaki K, Morishita R, Hashimoto N. domains. Biochemistry 2008;47:1442‑51.
NF‑kappaB is a key mediator of cerebral aneurysm formation. 42. Stefansson B, Brautigan DL. Protein phosphatase 6 subunit with
Circulation 2007;116:2830‑40. conserved Sit4‑associated protein domain targets IkappaBepsilon.
28. Aoki T, Kataoka H, Ishibashi R, Nozaki K, Morishita R, Hashimoto N. J Biol Chem 2006;281:22624‑34.
Reduced collagen biosynthesis is the hallmark of cerebral aneurysm: 43. Nakaoka H, Tajima A, Yoneyama T, Hosomichi K, Kasuya H,
contribution of interleukin‑1beta and nuclear factor‑kappaB. Mizutani T, Inoue I. Gene expression profiling reveals distinct
Arterioscler Thromb Vasc Biol 2009;29:1080‑6. molecular signatures associated with the rupture of intracranial
29. Nahed BV, Bydon M, Ozturk AK, Bilguvar K, Bayrakli F, Gunel M. aneurysm. Stroke 2014;45:2239‑45.
Genetics of intracranial aneurysms. Neurosurgery 2007;60:213‑25. 44. Nayak L, Lin Z, Jain MK. “Go with the flow”: how Krüppel‑like
30. Rinkel GJ, Djibuti M, Algra A, van Gijn J. Prevalence and risk factor 2 regulates the vasoprotective effects of shear stress. Antioxid
of rupture of intracranial aneurysms: a systematic review. Stroke Redox Signal 2011;15:1449‑61.
1998;29:251‑6. 45. Weinsheimer SM, Xu H, Achrol AS, Stamova B, McCulloch CE,
31. Bilguvar K, Yasuno K, Niemelä M, Ruigrok YM, von Und Zu Pawlikowska L, Tian Y, Ko NU, Lawton MT, Steinberg GK,
Fraunberg M, van Duijn CM, van den Berg LH, Mane S, Mason CE, Chang SD, Jickling G, Ander BP, Kim H, Sharp FR, Young WL. Gene
Choi M, Gaal E, Bayri Y, Kolb L, Arlier Z, Ravuri S, Ronkainen A, expression profiling of blood in brain arteriovenous malformation
Tajima A, Laakso A, Hata A, Kasuya H, Koivisto T, Rinne J, patients. Transl Stroke Res 2011;2:575‑87.
Ohman J, Breteler MM, Wijmenga C, State MW, Rinkel GJ, 46. Giusti B, Rossi L, Lapini I, Magi A, Pratesi G, Lavitrano M, Biasi GM,
Hernesniemi J, Jaaskelainen JE, Palotie A, Inoue I, Lifton RP, Pulli R, Pratesi C, Abbate R. Gene expression profiling of peripheral
Gunel M. Susceptibility loci for intracranial aneurysm in European blood in patients with abdominal aortic aneurysm. Eur J Vasc
and Japanese populations. Nat Genet 2008;40:1472‑7. Endovasc Surg 2009;38:104‑12.
32. Yasuno K, Bilguvar K, Bijlenga P, Low SK, Krischek B, Auburger G, 47. Pera J, Korostynski M, Golda S, Piechota M, Dzbek J, Krzyszkowski T,
Simon M, Krex D, Arlier Z, Nayak N, Ruigrok YM, Niemela M, Dziedzic T, Moskala M, Przewlocki R, Szczudlik A, Slowik A. Gene
Tajima A, von und zu Fraunberg M, Doczi T, Wirjatijasa F, Hata A, expression profiling of blood in ruptured intracranial aneurysms: in
Blasco J, Oszvald A, Kasuya H, Zilani G, Schoch B, Singh P, search of biomarkers. J Cereb Blood Flow Metab 2013;33:1025‑31.
Stuer C, Risselada R, Beck J, Sola T, Ricciardi F, Aromaa A, Illig T, 48. Weissleder R, Nahrendorf M, Pittet MJ. Imaging macrophages with
Schreiber S, van Duijn CM, van den Berg LH, Perret C, Proust C, nanoparticles. Nat Mater 2014;13:125‑38.
Roder C, Ozturk AK, Gaal E, Berg D, Geisen C, Friedrich CM, 49. Hasan DM, Mahaney KB, Magnotta VA, Kung DK, Lawton MT,
Summers P, Frangi AF, State MW, Wichmann HE, Breteler MM, Hashimoto T, Winn HR, Saloner D, Martin A, Gahramanov S,
Wijmenga C, Mane S, Peltonen L, Elio V, Sturkenboom MC, Dosa E, Neuwelt E, Young WL. Macrophage imaging within human
Lawford P, Byrne J, Macho J, Sandalcioglu EI, Meyer B, Raabe A, cerebral aneurysms wall using ferumoxytol‑enhanced MRI: a pilot
Steinmetz H, Rufenacht D, Jaaskelainen JE, Hernesniemi J, study. Arterioscler Thromb Vasc Biol 2012;32:1032‑8.
Rinkel GJ, Zembutsu H, Inoue I, Palotie A, Cambien F, Nakamura Y, 50. Hasan DM, Amans M, Tihan T, Hess C, Guo Y, Cha S, Su H,
Lifton RP, Gunel M. Genome‑wide association study of intracranial Martin AJ, Lawton MT, Neuwelt EA, Saloner DA, Young WL.
aneurysm identifies three new risk loci. Nat Genet 2010;42:420‑5. Ferumoxytol‑enhanced MRI to image inflammation within human
33. Alg VS, Sofat R, Houlden H, Werring DJ. Genetic risk factors for brain arteriovenous malformations: a pilot investigation. Transl
intracranial aneurysms: a meta‑analysis in more than 116,000 Stroke Res 2012;3:166‑73.
individuals. Neurology 2013;80:2154‑65. 51. Hasan D, Chalouhi N, Jabbour P, Dumont AS, Kung DK,
34. Bakir‑Gungor B, Sezerman OU. The identification of pathway Magnotta VA, Young WL, Hashimoto T, Winn HR, Heistad D. Early

84 Neuroimmunol Neuroinflammation | Volume 2 | Issue 2 | April 15, 2015