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change in ferumoxytol‑enhanced magnetic resonance imaging signal   58.  Hasan D, Hashimoto T, Kung D, Macdonald RL, Winn HR, Heistad D.
              suggests unstable human cerebral aneurysm: a pilot study. Stroke   Upregulation of cyclooxygenase‑2  (COX‑2) and microsomal
              2012;43:3258‑65.                                    prostaglandin E2 synthase‑1 (mPGES‑1) in wall of ruptured human
           52.  Hasan  DM, Chalouhi  N,  Jabbour  P, Dumont  AS,  Kung  DK,   cerebral aneurysms: preliminary results. Stroke 2012;43:1964‑7.
              Magnotta VA, Young WL, Hashimoto T, Richard Winn H, Heistad D.   59.  Mehta PK, Griendling KK. Angiotensin II cell signaling: physiological
              Evidence that acetylsalicylic acid attenuates inflammation in the   and pathological effects in the cardiovascular system. Am J Physiol
              walls of human cerebral aneurysms: preliminary results. J Am Heart   Cell Physiol 2007;292:C82‑97.
              Assoc 2013;2:e000019.                           60.  Peña Silva  RA, Kung  DK, Mitchell  IJ, Alenina  N, Bader  M,
           53.  Chalouhi N, Jabbour P, Magnotta V, Hasan D. The emerging role of   Santos RA, Faraci FM, Heistad DD, Hasan DM. Angiotensin 1‑7
              ferumoxytol‑enhanced MRI in the management of cerebrovascular   reduces mortality and rupture of intracranial aneurysms in mice.
              lesions. Molecules 2013;18:9670‑83.                 Hypertension 2014;64:362‑8.
           54.  Hasan  DM, Chalouhi  N, Jabbour  P, Magnotta  VA, Kung  DK,   61.  Aoki  T, Kataoka  H, Nishimura  M, Ishibashi  R, Morishita  R,
              Young WL. Imaging aspirin effect on macrophages in the wall   Miyamoto S. Regression of intracranial aneurysms by simultaneous
              of human cerebral aneurysms using ferumoxytol‑enhanced MRI:   inhibition  of  nuclear  factor‑κB  and  Ets  with  chimeric  decoy
              preliminary results. J Neuroradiol 2013;40:187‑91.  oligodeoxynucleotide treatment. Neurosurgery 2012;70:1534‑43.
           55.  Gounis  MJ, Vedantham  S, Weaver  JP, Puri  AS, Brooks  CS,   62.  Starke RM, Chalouhi N, Jabbour PM, Tjoumakaris SI, Gonzalez LF,
              Wakhloo  AK, Bogdanov AA Jr. Myeloperoxidase in human   Rosenwasser RH, Wada K, Shimada K, Hasan DM, Greig NH,
              intracranial aneurysms: preliminary evidence.  Stroke   Owens GK, Dumont AS. Critical role of TNF‑α in cerebral aneurysm
              2014;45:1474‑7.                                     formation and progression to rupture.  J  Neuroinflammation
           56.  DeLeo MJ 3rd, Gounis  MJ, Hong  B, Ford  JC, Wakhloo  AK,   2014;11:77.
              Bogdanov AA Jr. Carotid artery brain aneurysm model: in vivo
              molecular enzyme‑specific MR imaging of active inflammation in a   Cite this article as: Dooley SA, Hudson JS, Hasan DM. Inflammation in
              pilot study. Radiology 2009;252:696‑703.         human cerebral aneurysms: pathogenesis, diagnostic imaging, genetics, and
           57.  Hasan DM, Mahaney KB, Brown RD Jr, Meissner I, Piepgras DG,   therapeutics. Neuroimmunol Neuroinflammation 2015;2(2):77-85.
              Huston J, Capuano AW, Torner JC. Aspirin as a promising agent   Source of Support: Nil. Conflict of Interest: No.
              for decreasing incidence of cerebral aneurysm rupture. Stroke
              2011;42:3156‑62.                                 Received: 14-09-2014; Accepted: 30-09-2014


























































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