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Salas et al. J Cancer Metastasis Treat 2018;4:15 I http://dx.doi.org/10.20517/2394-4722.2017.66 Page 11 of 13

DECLARATIONS
Acknowledgments
The authors would like to express their gratitude to Vladimir Flores for their support in staining preparation
of tumor sections.

Authors’ contributions
Conception and design of the study and performed data analysis and interpretation: Salas E, Castaneda CA,
Sanchez P, Postigo J
Performed data acquisition, as well as providing administrative, technical, and material support: Castillo M,
Villegas V, Postigo J, Cano L, Casavilca S, Bernabe LA, Villa-Robles MR, Mantilla R, Belmar C, Guerra H
Drafted the article and made critical revisions related to the intellectual content of the manuscript, and
approved the final version of the article to be published: all authors

Data source and availability
No additional data are available.

Financial support and sponsorship
None.

Conflicts of interest
There are no conflicts of interest.

Patient consent
Not applicable.

Ethics approval
The institutional review board approval was obtained from The Instituto Nacional de Enfermedades
Neoplasicas (Lima, Peru).

Copyright
© The Author(s) 2018.

REFERENCES
1. Binahmed A, Nason RW, Hussain A, Abdoh AA, Sandor GK. Treatment outcomes in squamous cell carcinoma of the maxillary alveolus
and palate: a population-based study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008;105:750-4.
2. Balasubramanian D, Ebrahimi A, Gupta R, Gao K, Elliott M, Palme CE, Clark JR. Tumour thickness as a predictor of nodal metastases in
oral cancer: comparison between tongue and floor of mouth subsites. Oral Oncol 2014;50:1165-8.
3. Morris LG, Patel SG, Shah JP, Ganly I. High rates of regional failure in squamous cell carcinoma of the hard palate and maxillary
alveolus. Head Neck 2011;33:824-30.
4. Ogura I, Kurabayashi T, Sasaki T, Amagasa T, Okada N, Kaneda T. Maxillary bone invasion by gingival carcinoma as an indicator of
cervical metastasis. Dentomaxillofac Radiol 2003;32:291-4.
5. Simental AA Jr, Johnson JT, Myers EN. Cervical metastasis from squamous cell carcinoma of the maxillary alveolus and hard palate.
Laryngoscope 2006;116:1682-4.
6. Montes DM, Schmidt BL. Oral maxillary squamous cell carcinoma: management of the clinically negative neck. J Oral Maxillofac Surg
2008;66:762-6.
7. Kruse AL, Gratz KW. Cervical metastases of squamous cell carcinoma of the maxilla: a retrospective study of 9 years. Head Neck Oncol
2009;1:28.
8. Mourouzis C, Pratt C, Brennan PA. Squamous cell carcinoma of the maxillary gingiva, alveolus, and hard palate: is there a need for
elective neck dissection? Br J Oral Maxillofac Surg 2010;48:345-8.
9. Lin HW, Bhattacharyya N. Survival impact of nodal disease in hard palate and maxillary alveolus cancer. Laryngoscope 2009;119:312-5.
10. Li Q, Wu D, Liu WW, Li H, Liao WG, Zhang XR, Liu ZM, Guo ZM, Liu XK. Survival impact of cervical metastasis in squamous cell
carcinoma of hard palate. Oral Surg Oral Med Oral Pathol Oral Radiol 2013;116:23-7.
11. Hashibe M, Brennan P, Benhamou S, Castellsague X, Chen C, Curado MP, Dal Maso L, Daudt AW, Fabianova E, Fernandez L, Wünsch-