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Page 8 of 13 Salas et al. J Cancer Metastasis Treat 2018;4:15 I http://dx.doi.org/10.20517/2394-4722.2017.66
A
1.0
0.8
Cumulative probability 0.6
0.4
0.2
T2-T3
0.0 T4 P = 0.039
0 12 24 36 48 60
Time (months)
B
1.0
0.8
Cumulative probability 0.6
0.4
0.2
PNI-
0.0 PNI+ P = 0.019
0 12 24 36 48 60
Time (months)
C 1.0
0.8
Cumulative probability 0.6
0.4
0.2
LVI-
0.0 LVI+ P = 0.021
0 12 24 36 48 60
Time (months)
Figure 2. Estimated curves of OS regarding clinical tumor (A), perineural infiltration (B) and lymphovascular infiltration (C). OS: overall
survival; PNI: perineural invasion; LVI: lymphovascular infiltration
of the hard palate found node involvement in more than 29% of the hard palate tumors. Neck recurrence
was predicted by the presence of fixed or contralateral node metastases, but not by the presence of nodal
metastasis itself. Size of the primary tumor and histological grade was significantly associated with survival,
