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Devarakonda et al. J Cancer Metastasis Treat 2017;3:100-4                           Journal of
           DOI: 10.20517/2394-4722.2017.19
                                                             Cancer Metastasis and Treatment

                                                                                               www.jcmtjournal.com
            Original Article                                                                    Open Access


           Impact of health care insurance on

           overall survival of patients with multiple

           myeloma and monoclonal gammopathy of

           undetermined significance



           Srinivas S. Devarakonda , Runhua Shi , Ellen Friday , Reinhold Munker , Jonathan Glass , Francesco Turturro 1,3
                                1
                                                                         2
                                                                                        1
                                                        1
                                            1
           1 Department of Medicine, Feist-Weiller Cancer Center, Louisiana State University Health Sciences Center, Shreveport, LA 71103, USA.
           2 Department of Medicine, Louisiana State University, New Orleans, LA 71103, USA.
           3 Department of Lymphoma/Myeloma, MD Anderson Cancer Center, Houston, TX 77030, USA.
           Correspondence to: Dr. Srinivas S. Devarakonda, Department of Medicine, Feist-Weiller Cancer Center, Louisiana State University Health
           Sciences Center, 1501 Kings Highway, Shreveport, LA 71103, USA. E-mail: sdeva1@lsuhsc.edu
           How to cite this article: Devarakonda SS, Shi R, Friday E, Munker R, Glass J, Turturro F. Impact of health care insurance on overall survival of
           patients with multiple myeloma and monoclonal gammopathy of undetermined significance. J Cancer Metastasis Treat 2017;3:100-4.
                                         ABSTRACT
            Article history:              Aim: Health care insurance improves access to care and thus outcome in patients with
            Received: 13-03-2017          solid tumors. Little information on the impact of health care insurance on hematological
            Accepted: 22-05-2017          malignancies including multiple myeloma exists. The authors aimed to analyze the effect
            Published: 09-06-2017         of health care insurance on the survival of patients with multiple myeloma (MM) and
                                          monoclonal  gammopathy  of  undetermined  significance  (MGUS)  at  Louisiana  State
            Key words:                    University Health Sciences Center in Shreveport, LA. Methods: Two hundred fifty seven
            Multiple myeloma,             patients were reviewed, of which 208 had MM and 49 had MGUS. Results: One hundred
            monoclonal gammopathy of      and seventy seven patients (69%) were funded and 80 (31%) were non-funded. Funded
            undetermined significance,    patients with MM had an overall survival (OS) of 6.2 years compared to 3.8 years for non-
            health care,                  funded patients (P < 0.001). Survivals were not significantly affected by race or gender. The
            health insurance,             analysis demonstrates that funded patients with MM and MGUS patients have statistically
            outcomes,                     significant increased OS compared to patients with no insurance. Conclusion: This study
            survival                      showed that patients with multiple myeloma and MGUS with health care insurance have
                                          longer overall survival when compared to non-funded patients.


           INTRODUCTION                                       Americans. [1,2]  MM is preceded  by an asymptomatic
                                                              premalignant  proliferation  of plasma  cells  termed
           Multiple myeloma (MM) is the second most common    “monoclonal  gammopathy  of  uncertain  significance
           hematological malignancy in the United States and the   (MGUS)”. [3-6]  MM and MGUS are twice as common
           most common hematological malignancy  in  African-  in  African-Americans  as in Caucasians  and more

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