Page 81 - Read Online
P. 81
indirect-acting genotoxic agents in HepG2 cells. Food Chem Toxicol anti-proliferative and apoptotic effects of some novel tetrazolo[1,5-a]
2006;44:827-34. pyrimidine derivatives. Bioorg Med Chem 2010;18:2639-44.
9. Fleischauer AT, Arab L. Garlic and cancer: a critical review of the 30. Meng LH, Zhang H, Hayward L, Takemura H, Shao RG, Pommier Y.
epidemiologic literature. J Nutr 2001;131:S1032-40. Tetrandrine induces early G1 arrest in human colon carcinoma cells
10. Bottone FG Jr, Baek SJ, Nixon JB, Eling TE. Diallyl disulfi de (DADS) by down-regulating the activity and inducing the degradation of
induces the antitumorigenic NSAID-activated gene (NAG-1) by a G1-S-specific cyclin-dependent kinases and by inducing p53 and
p53-dependent mechanism in human colorectal HCT 116 cells. J Nutr p21Cip1. Cancer Res 2004;64:9086-92.
2002;132:773-8. 31. Chen Y, Miao ZH, Zhao WM, Ding J. The p53 pathway is synergized
11. Xiang SL, Xiao XL, Ling H, Liao QJ, Zhou XT, Dong L, Su Q. Antitumor by p38 MAPK signaling to mediate 11,11’-dideoxyverticillin-induced
effect of diallyl disulfi de on human gastric cancer MGC803 cells G2/M arrest. FEBS Lett 2005;579:3683-90.
xenograft in nude mice. Ai Zheng 2005;24:940-4. 32. Ianzini F, Bertoldo A, Kosmacek EA, Phillips SL, Mackey MA. Lack of
12. Yuan XK, Chen XQ, Jiang XY, Nie YL. Synthesis, characterization and p53 function promotes radiation-induced mitotic catastrophe in mouse
bioactivity of diallyl disulphide. J Cent S Univ Technol 2006;13:515-8. embryonic fi broblast cells. Cancer Cell Int 2006;6:11.
13. Freshney RI. Culture of Animal Cells: a Manual of Basic Technique. 33. Ahmed OM, Mohamed MA, Ahmed RR, Ahmed SA. Synthesis and
3rd ed. New York: Wiley; 1994. anti-tumor activities of some new pyridines and pyrazolo[1,5-a]
14. Freitas ES, Leite ED, Silva AE, Ocarino NM, Ferreira E, Gomes MG, pyrimidines. Eur J Med Chem 2009;44:3519-23.
Cassali GD, Serakides R. Effect of thyroxine and propylthiouracil in 34. Deng Y, Wu X. Peg3/Pw1 promotes p53-mediated apoptosis by inducing
Ehrlish asitic tumor cells. Int J Morphol 2006;24:665-71. Bax translocation from cytosol to mitochondria. Proc Natl Acad Sci
15. Chandru H, Sharada AC, Bettadaiah BK, Kumar CS, Rangappa KS, U S A 2000;97:12050-5.
Sunila, Jayashree K. In vivo growth inhibitory and anti-angiogenic 35. Knowles LM, Milner JA. Possible mechanism by which allyl sulfi des
effects of synthetic novel dienone cyclopropoxy curcumin analogs on suppress neoplastic cell proliferation. J Nutr 2001;131:S1061-6.
mouse Ehrlich ascites tumor. Bioorg Med Chem 2007;15:7696-703. 36. Robert V, Mouillé B, Mayeur C, Michaud M, Blachier F. Effects of the
16. Warren L. The thiobarbituric acid assay of sialic acids. J Biol Chem garlic compound diallyl disulfi de on the metabolism, adherence and cell
1959;234:1971-5. cycle of HT-29 colon carcinoma cells: evidence of sensitive and resistant
17. Negoescu A, Lorimier P, Labat-Moleur F, Drouet C, Robert C, sub-populations. Carcinogenesis 2001;22:1155-61.
Guillermet C, Brambilla C, Brambilla E. In situ apoptotic cell labeling by 37. Oommen S, Anto RJ, Srinivas G, Karunagaran D. Allicin (from garlic)
the TUNEL method: improvement and evaluation on cell preparations. induces caspase-mediated apoptosis in cancer cells. Eur J Pharmacol
J Histochem Cytochem 1996;44:959-68. 2004;485:97-103.
18. Gao H, Zhou YW. Inhibitory effect of picroside II on hepatocyte 38. Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med
apoptosis. Acta Pharmacol Sin 2005;26:729-36. 1971;285:1182-6.
19. Ahmed OM, Ahmed RR. Anti-proliferative and apoptotic effi cacies of 39. Risau W. Mechanisms of angiogenesis. Nature 1997;386:671-4.
ulvan polysaccharides against different types of carcinoma cells in vitro 40. Bergers G, Benjamin LE. Tumorigenesis and the angiogenic switch. Nat
and in vivo. J Cancer Sci Ther 2014;6:202-8. Rev Cancer 2003;3:401-10.
20. Rao M, Blane K, Zonneberg M. PC-STAT programs, version 1A (C), 41. Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS, Dvorak HF.
one and two way analysis of variance. Athens, GA: The University of Tumor cells secrete a vascular permeability factor that promotes
Georgia; 1985. accumulation of ascites fl uid. Science 1983;219:983-5.
21. Arican G, Arican E. Evaluation of the apoptotic and anti-proliferative 42. Funasaka T, Haga A, Raz A, Nagase H. Tumor autocrine motility
activities of paclitaxel in Ehrlish ascites tumor cells. Biotechnol factor induces hyperpermeability of endothelial and mesothelial cells
Biotechnol Equip 2006;20:69-75. leading to accumulation of ascites fl uid. Biochem Biophys Res Commun
22. Ozen N, Uslu E, Ozen M, Aydin S, Altug T, Belce A, Kokoglu E. 2002;293:192-200.
Curcumin’s effects on sialic acid level and sialidase activity in Ehrlich 43. Iciek MB, Rokita HB, Wlodek LB. Effects of diallyl disulfi de and other
ascites tumor bearing mice. Tohoku J Exp Med 2002;197:221-7. donors of sulfane sulfur on the proliferation of human hepatoma cell
23. Kuttan G, Kuttan R. Effect of diallyl sulphide, diallyl disulphide, and line (HepG2). Neoplasma 2001;48:307-12.
allyl methyl sulphide on the inhibition of lung metastasis of B16F-10 44. De Martino A, Filomeni G, Aquilano K, Ciriolo MR, Rotilio G. Effects
melanoma cells in mice. J Clin Biochem Nutr 1999;27:131-9. of water garlic extracts on cell cycle and viability of HepG2 hepatoma
24. Vijay V, Vickram, Raiker VG, Kashinath RT. Effect of diallyl disulphide cells. J Nutr Biochem 2006;17:742-9.
on renal glycated proteins and plasma sialic acid levels in alloxan diabetic 45. Ahmed OM, Abdel-Aleem SR, Mossa NM. Chemopreventive effect of
rats. Glob J Med Res 2011;11:31-5. diallyl disulphide on CCl -induced liver injury in albino rats. J Egypt
4
25. Gunadharini DN, Arunkumar A, Krishnamoorthy G, Muthuvel R, Ger Soc Zool 2008;56A: 25-62.
Vijayababu MR, Kanagaraj P, Srinivasan N, Aruldhas MM, Arunakaran J. 46. Abdel-Aleem SR, Ahmed OM, Mossa NM. Chemopreventive effects
Antiproliferative effect of diallyl disulfi de (DADS) on prostate cancer of diallyl disulphide on CCl -induced kidney injury and haematological
4
cell line LNCaP. Cell Biochem Funct 2006;24:407-12. disturbances in albino rats. J Egypt Ger Soc Zool 2007;55C: 389-419.
26. Sriram N, Kalayarasan S, Ashokkumar P, Sureshkumar A, Sudhandiran G. 47. García A, Haza AI, Arranz N, Delgado ME, Rafter J, Morales P.
Diallyl sulfi de induces apoptosis in Colo 320 DM human colon cancer Organosulfur compounds alone or in combination with vitamin C
cells: involvement of caspase-3, NF-kappaB, and ERK-2. Mol Cell protect towards N-nitrosopiperidine- and N-nitrosodibutylamine-induced
Biochem 2008;311:157-65. oxidative DNA damage in HepG2 cells. Chem Biol Interact 2008;173:9-18.
27. Mondal S, Bandyopadhyay S, Ghosh MK, Mukhopadhyay S, Roy S,
Mandal C. Natural products: promising resources for cancer drug How to cite this article: Ahmed OM, Ahmed RR. Anti-proliferative and
discovery. Anticancer Agents Med Chem 2012;12:49-75. apoptotic effi cacy of diallyl disulfi de on Ehrlich ascites carcinoma. Hepatoma
28. Bhattacharyya A, Choudhuri T, Pal S, Chattopadhyay S, Datta GK, Sa G, Res 2015;1:67-74.
Das T. Apoptogenic effects of black tea on Ehrlich’s ascites carcinoma
cell. Carcinogenesis 2003;24:75-80.
29. Hussein AM, Ahmed OM. Regioselective one-pot synthesis and Source of Support: Nil. Confl ict of Interest: None declared.
74 Hepatoma Research | Volume 1 | Issue 2 | July 15, 2015