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Stott et al. Art Int Surg 2023;3:207-16                                         Artificial
               DOI: 10.20517/ais.2022.42
                                                                               Intelligence Surgery



               Review                                                                        Open Access



               Can 3D visualisation and navigation techniques
               improve pancreatic surgery? A systematic review


                          1,2
               Martyn Stott , Ambareen Kausar 3
               1
                Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool L69 3GE, UK.
               2
                Department of Pancreatic Surgery, Royal Liverpool University Hospital, Liverpool L7 8YE, UK.
               3
                Department of HPB Surgery, Royal Blackburn Teaching Hospital, Blackburn BB2 3HH, UK.
               Correspondence to: Dr. Ambareen Kausar, Department of HPB Surgery, Royal Blackburn Teaching Hospital, East Lancashire
               Hospitals NHS Trust, Haslingden Road, Blackburn BB2 3HH, UK. E-mail: ambareen@doctors.org.uk

               How to cite this article: Stott M, Kausar A. Can 3D visualisation and navigation techniques improve pancreatic surgery? A
               systematic review. Art Int Surg 2023;3:207-16. https://dx.doi.org/10.20517/ais.2022.42

               Received: 26 Dec 2022  First Decision: 6 Mar 2023  Revised: 5 Jul 2023  Accepted: 19 Oct 2023  Published: 25 Oct 2023
               Academic Editors: Derek O’Reilly, Andrew Gumbs  Copy Editor: Pei-Yun Wang  Production Editor: Pei-Yun Wang


               Abstract
               Pancreatic cancer, namely pancreatic ductal adenocarcinoma (PDAC), is an intractable cancer with a 5-year
               survival of around 7%-10%. Surgery with adjuvant chemotherapy remains the mainstay of curative treatment. The
               pancreas is a retroperitoneal organ that lies close to major arterial and venous structures, and it is the involvement
               of these structures that currently technically limits surgical resection with curative intent for pancreatic cancer. It is
               possible to resect venous and arterial structures involved in cancer to expand options for patients for whom
               surgery was previously deemed infeasible, but this is best performed in high-volume pancreatic surgery centres.
               Here, we explore the role that 3D visualisation and navigation surgery have in improving preoperative planning and
               operative execution, the role they may play in training and education and in enabling the development of novel
               surgical techniques in pancreatic surgery.

               Keywords: 3D-visualisation, navigation surgery, cinematic rendering simulation, pancreatic surgery



               INTRODUCTION
               Pancreatic cancer, namely pancreatic ductal adenocarcinoma (PDAC), is an intractable cancer with a 5-year
               survival of around 7%-10% . Surgery with adjuvant chemotherapy remains the mainstay of curative
                                       [1,2]
                       [3]
               treatment . The pancreas is a retroperitoneal organ that lies close to major arterial and venous structures,





                           © The Author(s) 2023. Open Access This article is licensed under a Creative Commons Attribution 4.0
                           International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing,
                           adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as
               long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and
               indicate if changes were made.

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