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Page 4 of 13                                                          Sun et al. Vessel Plus 2020;4:13  I  http://dx.doi.org/10.20517/2574-1209.2020.02
































                               Figure 2. Distribution of test points for a two-factor general rotating combination design


               Table 1. Coding factors for abdominal aortic aneurysm models designed for males and females and corresponding values
                                                                    Coded levels
                Factors
                                          -r (-1.682)     -1            0            +1         +r (1.682)
                Diameter (mm)  Male          30           36.1         45            53.9         60
                               Female        27           31.7         38.5          45.3         50
                Asymmetry index              0.3          0.44         0.65          0.86         1
                Wall thickness (mm)          0.8          1.08         1.5           1.92         2.2


               Table 2. Design matrix as well as simulated and predicted peak wall stresses for the abdominal aortic aneurysm models
               designed for males
                Test model   Maximum diameter                              Simulated peak wall   Predicted peak wall
                (male)       D max  (mm)  Asymmetry index β  Wall thickness t (mm)  stress (KPa)  stress (KPa)
                1             1 (53.9)         1 (0.86)        1 (1.92)        273.85          276.29
                2             1 (53.9)         1 (0.86)        -1 (1.08)       531.13          533.65
                3             1 (53.9)         -1 (0.44)       1 (1.92)        415.19          415.67
                4             1 (53.9)         -1 (0.44)       -1 (1.08)       822.74          823.11
                5             -1 (36.1)        1 (0.86)        1 (1.92)        167.33          178.41
                6             -1 (36.1)        1 (0.86)        -1 (1.08)       326.61          337.61
                7             -1 (36.1)        -1 (0.44)       1 (1.92)        267.29          276.23
                8             -1 (36.1)        -1 (0.44)       -1 (1.08)       576.48          585.51
                9             r (60)           0 (0.65)        0 (1.5)         487.86          489.81
                10            -r (30)          0 (0.65)        0 (1.5)         225.48          207.67
                11            0 (45)           r (1)           0 (1.5)         257.02          245.41
                12            0 (45)           -r (0.3)        0 (1.5)         574.79          571.11
                13            0 (45)           0 (0.65)        r (2.2)         228.5           220.15
                14            0 (45)           0 (0.65)        -r (0.8)        820.63          817.73
                15            0 (45)           0 (0.65)        0 (1.5)         374.61          375.67
                16            0 (45)           0 (0.65)        0 (1.5)         374.73          375.67
                17            0 (45)           0 (0.65)        0 (1.5)         371.05          375.67
                18            0 (45)           0 (0.65)        0 (1.5)         372.17          375.67
                19            0 (45)           0 (0.65)        0 (1.5)         378.92          375.67
                20            0 (45)           0 (0.65)        0 (1.5)         379.23          375.67
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