Page 187 - Read Online
P. 187
Page 20 of 21 Bradshaw et al. Vessel Plus 2023;7:35 https://dx.doi.org/10.20517/2574-1209.2023.121
119. Hanley PJ, Mickel M, Löffler M, Brandt U, Daut J. K ATP channel-independent targets of diazoxide and 5-hydroxydecanoate in the
heart. J Physiol 2002;542:735-41. DOI PubMed PMC
120. Dzeja PP, Bast P, Ozcan C, et al. Targeting nucleotide-requiring enzymes: implications for diazoxide-induced cardioprotection. Am J
Physiol Heart Circ Physiol 2003;284:1048-56. DOI
121. Ockaili RA, Bhargava P, Kukreja RC. Chemical preconditioning with 3-nitropropionic acid in hearts: role of mitochondrial K
ATP
channel. J Physiol Heart Circ Physiol 2001;280:2406-11. DOI PubMed
122. Busija DW, Katakam P, Rajapakse NC, et al. Effects of ATP-sensitive potassium channel activators diazoxide and BMS-191095 on
membrane potential and reactive oxygen species production in isolated piglet mitochondria. Brain Res Bull 2005;66:85-90. DOI
123. Chouchani ET, Pell VR, Gaude E, et al. Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.
Nature 2014;515:431-5. DOI
124. Anastacio MM, Kanter EM, Keith AD, Schuessler RB, Nichols CG, Lawton JS. Inhibition of succinate dehydrogenase by diazoxide
is independent of the ATP-sensitive potassium channel subunit sulfonylurea type 1 receptor. J Am Coll Surg 2013;216:1144-9. DOI
PubMed PMC
2+
125. Eaton M, Hernandez LA, Schaefer S. Ischemic preconditioning and diazoxide limit mitochondrial Ca overload during ischemia/
reperfusion: role of reactive oxygen species. Exp Clin Cardiol 2005;10:96-103. PubMed PMC
126. Ahmad T, Wang J, Velez AK, et al. Cardioprotective mechanisms of mitochondria-targeted S-nitrosating agent and adenosine
triphosphate-sensitive potassium channel opener are mutually exclusive. JTCVS Open 2021;8:338-54. DOI PubMed PMC
127. Uchiyama Y, Otani H, Okada T, et al. Integrated pharmacological preconditioning in combination with adenosine, a mitochondrial
K channel opener and a nitric oxide donor. J Thorac Cardiovasc Surg 2003;126:148-59. DOI
ATP
128. Kim MY, Kim MJ, Yoon IS, et al. Diazoxide acts more as a PKC-epsilon activator, and indirectly activates the mitochondrial K
ATP
channel conferring cardioprotection against hypoxic injury. Br J Pharmacol 2006;149:1059-70. DOI PubMed PMC
129. Akao M, Ohler A, O’rourke B, Marbán E. Mitochondrial ATP-sensitive potassium channels inhibit apoptosis induced by oxidative
stress in cardiac cells. Circ Res 2001;88:1267-75. DOI PubMed
130. Yonemochi H, Ichinose M, Anan F, et al. Diazoxide-induced cardioprotection via DeltaPsim loss depending on timing of application.
Life Sci 2006;79:1906-12. DOI
131. Mccully JD, Wakiyama H, Cowan DB, Federman M, Parker RA, Levitsky S. Diazoxide amelioration of myocardial injury and
mitochondrial damage during cardiac surgery. Ann Thorac Surg 2002;74:2138-46. DOI PubMed PMC
132. Maslov LN, Popov SV, Naryzhnaya NV, et al. K channels are regulators of programmed cell death and targets for the creation of
ATP
novel drugs against ischemia/reperfusion cardiac injury. Fundam Clin Pharmacol 2023;37:1020-49. DOI
133. Davies JE, Digerness SB, Killingsworth CR, et al. Multiple treatment approach to limit cardiac ischemia-reperfusion injury. Ann
Thorac Surg 2005;80:1408-16. DOI
134. Makepeace CM, Suarez-Pierre A, Kanter EM, Schuessler RB, Nichols CG, Lawton JS. Superior diastolic function with K ATP channel
opener diazoxide in a novel mouse Langendorff model. J Surg Res 2018;227:186-93. DOI PubMed PMC
135. Suarez-Pierre A, Lui C, Zhou X, et al. Diazoxide preserves myocardial function in a swine model of hypothermic cardioplegic arrest
and prolonged global ischemia. J Thorac Cardiovasc Surg 2022;163:e385-400. DOI
136. Velez AK, Etchill E, Giuliano K, et al. ATP - sensitive potassium channel opener diazoxide reduces myocardial stunning in a porcine
regional with subsequent global ischemia model. J Am Heart Assoc 2022;11:e026304. DOI PubMed PMC
137. Wang X, Wei M, Kuukasjärvi P, et al. Novel pharmacological preconditioning with diazoxide attenuates myocardial stunning in
coronary artery bypass grafting. Eur J Cardiothorac Surg 2003;24:967-73. DOI
138. Deja MA, Malinowski M, Gołba KS, et al. Diazoxide protects myocardial mitochondria, metabolism, and function during cardiac
surgery: a double-blind randomized feasibility study of diazoxide-supplemented cardioplegia. J Thorac Cardiovasc Surg
2009;137:997-1004. DOI
139. Ziganshin BA, Elefteriades JA. Deep hypothermic circulatory arrest. Ann Cardiothorac Surg 2013;2:303-15. DOI PubMed PMC
140. Wang X, Yang F, Zhu J, Liu Y, Sun L, Hou X. Aortic arch surgery with hypothermic circulatory arrest and unilateral antegrade
cerebral perfusion: perioperative outcomes. J Thorac Cardiovasc Surg 2020;159:374-87.e4. DOI
141. Bergeron EJ, Mosca MS, Aftab M, Justison G, Reece TB. Neuroprotection strategies in aortic surgery. Cardiol Clin 2017;35:453-65.
DOI PubMed
142. Giuliano K, Etchill E, Velez AK, et al. Ketamine mitigates neurobehavioral deficits in a canine model of hypothermic circulatory
arrest. Semin Thorac Cardiovasc Surg 2023;35:251-8. DOI PubMed PMC
2+
+
143. Honrath B, Krabbendam IE, Culmsee C, Dolga AM. Small conductance Ca -activated K channels in the plasma membrane,
mitochondria and the ER: pharmacology and implications in neuronal diseases. Neurochem Int 2017;109:13-23. DOI PubMed
144. Debska G, May R, Kicinska A, Szewczyk A, Elger CE, Kunz WS. Potassium channel openers depolarize hippocampal mitochondria.
Brain Res 2001;892:42-50. DOI PubMed
145. De Arriba S, Franke H, Pissarek M, Nieber K, Illes P. Neuroprotection by ATP-dependent potassium channels in rat neocortical brain
slices during hypoxia. Neurosci Lett 1999;273:13-6. DOI PubMed
146. Domoki F, Perciaccante JV, Veltkamp R, Bari F, Busija DW. Mitochondrial Potassium channel opener diazoxide preserves neuronal-
vascular function after cerebral ischemia in newborn pigs. Stroke 1999;30:2713-9. DOI PubMed
147. Barreiro CJ, Williams JA, Fitton TP, et al. Noninvasive assessment of brain injury in a canine model of hypothermic circulatory arrest
using magnetic resonance spectroscopy. Ann Thorac Surg 2006;81:1593-8. DOI