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Page 12 of 17                   Hong et al. Vessel Plus 2022;6:4  https://dx.doi.org/10.20517/2574-1209.2021.88

               Distal anastomosis
               When a four-branched replacement graft is used, the distal anastomosis is performed before reattachment
               of the visceral and renal arteries to re-establish flow to the lower extremities while the visceral and renal
               organs continue to be perfused via the LHB and renal cooling circuit, respectively [Figure 10]. The distal
               aortic anastomosis is usually sewn at the level of the aortic bifurcation but can be anastomosed to the iliac or
               femoral arteries, using additional grafts as needed. If the chronic dissection extends distally, the septum is
               fenestrated to ensure downstream perfusion into both lumens. The aortic graft is cut to a suitable length to
               prevent kinking or tension, and a 3-0 polypropylene suture is used in a continuous fashion to complete the
               anastomosis. As before, felt-pledgeted mattress sutures are used to reinforce the anastomosis.


               The patient is then placed in the Trendelenburg position, and a 19-gauge needle is used to create deairing
               holes in the Dacron graft. Individual clamps are placed on each of the four branches of the prefabricated
               graft. The aorta is deaired through one of the branches of the graft. The aortic cross-clamp is slowly
               removed to reestablish blood flow to the lower body. Anesthesia facilitates patient resuscitation to maintain
               MAP after cross-clamp removal; typically, the use of bicarbonate and vasopressors is necessary.


               Visceral and renal anastomosis with a four-branched graft
               The ostia of the celiac, SMA, and renal arteries are isolated on buttons of aortic tissue and are carefully
               inspected for extension of dissection as well as for calcium or stenosis related to the atherosclerotic process.
               Endarterectomy, decalcification, or direct stenting (usually with a 7-mm × 15-mm balloon-expandable
               stent) may be required. If the dissection extends into the visceral arteries, fenestration may be necessary to
               ensure the perfusion of both lumens. The perfusion catheters are maintained to limit ischemic time. Because
               the right renal artery is most posterior, it is sewn first; we use a 4-0 or 5-0 polypropylene suture [Figure 11].
               The anastomosis is deaired, and the clamp is released to reestablish perfusion. Then, the SMA and celiac
               axis anastomoses are carried out. We typically leave the SMA clamped during the celiac axis anastomosis to
               prevent back-bleeding through collateral arteries, which affects visualization. The left renal artery
               anastomosis is typically sewn last. The inferior mesenteric artery is usually oversewn, but reimplantation
               may be necessary if bilateral hypogastric artery occlusions, previous colectomy, or a diseased SMA are
               present.

               Hemostasis and closure
               In preparation for closure, the four-branched graft is inspected for malorientation, kinks, or twists. The
               femoral arteries, renal arteries, celiac axis, and SMA [Figure 12] are palpated for a distal pulse, and the
               kidneys are palpated for turgor. The bowel is visualized to confirm its perfusion. The spleen is inspected for
               any hematoma or laceration; any splenic injury that cannot be controlled with electrocautery or packing
               necessitates a splenectomy to avoid potential bleeding complications. The patient’s temperature is passively
               rewarmed to > 34.5 °C. We confirm the position of the nasogastric tube before closure. An abdominal drain
               is placed in the retroperitoneal space. The left hemidiaphragm is reapproximated under tension by using a
               #1 polypropylene continuous suture that is locked every three bites. Two chest tubes are placed,
               anterosuperiorly and posteroinferiorly. Absorbable pericostal sutures are placed in and around the ribs in a
               figure-of-eight, interrupted fashion with #2 coated braided polyester sutures. Two #7 steel wires are placed
               to secure the thoracotomy closure. The abdominal fascia is closed and tied to the diaphragmatic suture. Soft
               tissue is closed, and single-lung ventilation is discontinued.


               Postoperative care
               Critical care monitoring and volume resuscitation form the cornerstone of postoperative care in patients
               with a TAAA. The MAP is maintained at 80-100 mmHg, and the patient’s neurological status is checked
               every hour, particularly the patient’s leg strength. The patient’s hemoglobin level is kept above 10 g/dL to
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