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Tanikawa Plast Aesthet Res 2020;7:48  I  http://dx.doi.org/10.20517/2347-9264.2020.136                                         Page 13 of 16

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               Figure 12. Z-scores for the four categories (Code) of Cleft patients. The average shape was evaluated with the normative range [19] . Only
               the z-axis (anterior-posterior direction) results were exemplified. A grey profile indicates the average face. Z-score was calculated by
               the equation: Z-score  (z)  = (p (z)  - m (z) )/s  (z) ,  where p (z)  indicates the averaged coordinate values of each code, m (z)  indicates the average
               coordinate values of the control group, and s  (z)  indicates the standard deviation of the coordinate values of the control group in the
               z-direction. Please note that Code 1 shows that the anterior-posterior position of the upper and lower lips was within 1 SD. In Codes 2
               and 3, the cheeks (midface) were remarkably retruded, while the anterior-posterior position of the upper lip was within 1 SD. Codes 4
               shows greater protrusion of upper and lower lips

               Table 2. Demographic data in each code
                                                          Code 1       Code 2       Code 3       Code 4
                Patient number                             17           15           14           14
                Sex
                     Male                                  1            13           11           11
                     Female                                16           2            3            3
                Cleft side
                     Left                                  11           13           11           11
                     Right                                 6            2            3            3
                Orthodontic treatment
                     Camouflage                            4            4            2            3
                     Surgery                               13           11           12           11
                Surgical technique for the palatoplasty
                     Wardill-Kilner push-back              15           15           12           12
                     Early two-stage with modified Furlow veloplasty  2  0           2            2
                Age (years old)
                     Mean                                  20.6         21.9         22.2         23.5
                     Standard deviation                    3.2          2.3          7.5          5.6


               remained, even after surgery. This was considered to be due to treatment limitations. Another possibility
               is that there were no measures to analyze the 3D face when we had performed surgery. The method
               introduced in the present article helps both patients and orthodontists share a mutual understanding of the
               soft tissue problems of patients with CLP. The patient’s facial soft tissues can be quantified and visualized
               three-dimensionally. This is useful for developing optimum treatment plans based on the evaluation of soft
               tissue.
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