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Rampino Cordaro et al. Plast Aesthet Res 2017;4:24-31 Plastic and
DOI: 10.20517/2347-9264.2016.52
Aesthetic Research

www.parjournal.net
Original Article Open Access

A study of correlation between prosthetic

breast reconstruction, antibiotic prophylaxis

and surgical wound drains

Emanuele Rampino Cordaro , Nicola Zerbinati , Alice Garzitto , Daria Almesberger , Michela Francescon ,
1
1
1
2
1
Raffaele Rauso , Mario Cherubino , Pier Camillo Parodi
3
4
1
1 Department of Plastic Reconstructive Surgery, University of Udine, 33100 Udine, Italy.
2 Department of Surgical and Morphological Sciences, University of Insubria, 21100 Varese, Italy.
3 Department of Dentistry, University of Foggia, 71121 Foggia, Italy.
4 Department of Biotechnology and Science of Life, University of Insubria, 21100 Varese, Italy.
Correspondence to: Dr. Emanuele Rampino Cordaro, Plastic Surgery Department, Santa Maria della Misericordia Hospital, Santa Maria della
Misericordia Place 15, 33100 Udine, Italy. E-mail: emanuele.rampino@uniud.it
How to cite this article: Rampino Cordaro E, Zerbinati N, Garzitto A, Almesberger D, Francescon M, Rauso R, Cherubino M, Parodi PC. A study
of correlation between prosthetic breast reconstruction, antibiotic prophylaxis and surgical wound drains. Plast Aesthet Res 2017;4:24-31.
Dr. Emanuele Rampino Cordaro was born in Udine (Italy) on 30th September, 1971 and graduated in Medicine and
Surgery at the University of Udine on September 1996. He was specialized in Plastic Reconstructive Surgery at the
University of Udine on November 2002. After several training experiences in Italy and abroad, he has been enrolled
at the University Hospital “Santa Maria della Misericordia” in Udine (Italy) on December 2005, as Consultant Plastic
Surgeon. He is author and co-author of several publications on national and international journals, covering the main
fields of plastic reconstructive and aesthetic surgery.

ABSTRACT
Article history: Aim: The primary aim of this investigation into the correlation between prosthetic breast
Received: 10-07-2016 reconstruction, antibiotic prophylaxis and surgical drains was to determine whether the
Accepted: 23-01-2017 short-term prophylaxis recommended in the current guidelines is in fact able to sterilize
Published: 28-02-2017 the peri-prosthetic pocket in patients undergoing prosthetic breast reconstruction via tissue
expansion, permanent implant placement, or Becker implants, as well as augmentation to
Key words: correct symmetry. Methods: A total of 96 women who had undergone prosthetic breast
Breast implant, reconstruction surgery were considered. Patients were recruited from the Plastic Surgery
antibiotic prophylaxis, Clinic, Gemona, and the Surgery Clinic, Udine, both affiliated with the Udine “Santa Maria
drains, della Misericordia” University Hospital between May 2013 and May 2014. All patients
infections, were administered the recommended short-term antibiotic prophylaxis, i.e. 2 g cephazolin
breast reconstruction (plus 1 g eventually given after 3.5 h of surgery) 30 min before surgery. Records pertaining
to each patient were kept in a specific study chart. Results: Samples of peri-prosthetic
drainage fluid were taken from 92.5% of the recipients of breast reconstruction/implant
surgery. Only 2.3% of the samples analyzed were found to be positive for microbial strains.
Conclusion: The results of this preliminary study are encouraging, demonstrating that the
guidelines regarding short-term antibiotic prophylaxis are indeed effective.

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