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Rosen et al.                                                                                                                                                       Barbed vs. smooth suture for periareolar closure
























           Figure 3: Intra operative photo with interlocking purse-string barbed   Figure 4: The final intra operative appearance of the 2-layer
           suture prior to cinching (outlined diagrammatically in Figure 2 above).  absorbable barbed suture closure as described
           (PGA-PCL) for subcuticular layer. Monoderm™ retains   and complications. Both pre- and postoperative photos
           62% of its original tensile strength at 7 days, and 27% at   were  taken  with  Mirror  Image  Software  (Canfield
           14 days, with absorption essentially complete within 90-  Scientific  Corp,  Fairfield,  NJ).  Surgical  areola  marker
           120 days, while the longer-term PDO™ retains 50-80%   size was obtained from operative report review. Follow-
           of its original tensile strength at 4 weeks, with absorption   up assessments were based on photos taken between 6
           essentially complete within 180 days. [13,14]      and 24 months postoperatively, and postoperative areola
                                                              sizes were measured using free digital photo software
           We  selected  a  patient  population  specifically  to  limit   (GNU  Image  Manipulation  Program/www.gimp.org).
           variables related to skin tension forces. We, therefore,   Areolar width and height measurements were completed
           excluded  reduction mammoplasty and  augmentation   using the GIMP software.
           mastopexy and focused solely on patients undergoing
           mastopexy alone.  The study population was further   The  primary  outcome  was  the  change  from  baseline
           limited  to  patients  with  postoperative  photographs   areolar  template  size  used  and  the  photometrically
           between 6 months and 24 months after the mastopexy   measured postoperative areola size.  T-test statistics
           to minimize variables associated with aging.       were used to compare within group pre-operative areola
                                                              size with postoperative areola size. Analysis of variance
           The final analysis was performed on 20 eligible patients   (ANOVA) was used to compare change from baseline
           (40 breasts) in whom closures were performed using   scores between groups, using XLSTAT software,
           absorbable barbed suture exclusively. Since no previous   Version 2014.5.01. This later test was considered to be
           reports of areolar spread  rates have been  published,   the preferred test to assess changes from baseline in
           for comparison purposes, we assessed 12 eligible   studies with a non-randomized design.  The incidence
                                                                                               [15]
           patients (24 breasts) in whom mastopexy closures were   of complications was considered a secondary outcome.
           performed  with  ePTFE/Monocryl.  The  primary  author
           performed all surgeries using the same circumvertical   RESULTS
           technique  at the same surgical center. Diagrammatic
                    [4]
           representation of interlocking purse string technique is   The 32 patients assessed had a mean age of 41.6 years,
           demonstrated in  [Figure  1]. Intraoperative  photos are   and mean BMI of 23.5 kg/m . Patients whose mastopexy
                                                                                      2
           shown below depicting the periareolar wound, prior to   incisions were closed with absorbable barbed sutures
           suture deployment  [Figure  2], after suture placement   were similar in both age and mean BMI to those closed
           [Figure 3], and after final closure [Figure 4].    with permanent sutures [Table 1]. The two groups were
                                                              also similar in the incidence of hypertension, diabetes
           In the permanent suture group, a ligature was secured   and in the percentage that were current smokers. Many
           with a surgeons knot at the T-zone. Cinching of the suture   (12/32, 37.5%) had a history of other relevant medical
           was performed to the desired areolar size in both groups.   conditions. More subjects in the barbed suture closure
           Data were compiled for patient demographics [age,   group had undergone previous breast surgeries: 6/20,
           body mass index (BMI)], medical history (hypertension,   30.0% vs. 2/12, 16.7% in the ePTFE group.
           smoking status, diabetes, previous breast surgery),
           surgical record (technique used, additional procedures)   In 62.5% of cases (20/32), mastopexy was performed
            298                                                                                    Plastic and Aesthetic Research ¦ Volume 3 ¦ September 20, 2016
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