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Rajput Cyclical nutritional therapy clinical trial

80

70

60

50
Hair calibre in treatment group
40

Hair calibre in control group
30

20 Non responders in control group

10

0
2 months 4 months 6 months 12 months
Figure 8: Hair calibre in women

for both men and women were similar, the improvement placebo at 1 month, 34.5% at 2 months and 34.4%
started as a noticeable change in 2 months for over reduction in hair loss at 3 months [69] . Rizer et al. [70]
70% patients and progressed to good in all the patients who studied the benefit of marine protein supplement
by the end of 6 months, becoming very good by end of reported 20% reduced hair shedding within 4 months,
1 year. while the placebo group had increased shedding by
50%. Hair loss in control group continued the same
Self-assessment scores in 41% and increased in 37% patients at the end of
Self-assessment in treatment groups TM and TW had 4 months. Some relief from hair shedding seen in
scores of 4 seen in 70% men and 62% women noticing the control group may be due to the benefit of 2%
good hair growth within 4 months of commencing the minoxidil. A certain basic amount of steady hair fall
therapy. Whereas 49% men and 74% women had a did continue even in treatment group which can be
score of 5, reporting that their hair stylist, their family expected to happen as per the natural hair cycle.
and friends noticed the changes in their hair growth,
thickness and quality at the end of one year. The improvement in density and calibre in both the
male and female treatment groups were similar to
Self-assessment in the control groups CM and CW for improvement recorded by Beer et al. [69] as per their
[69]
all patients were poor, below 3. At the end of 1 year criteria for evaluation of hair quality. Beer et al. studied
had 64% men and 71% women said that they looked the benefits from a supplement of keratin with minerals
the same, had continued hair loss and could not and vitamins which showed an improvement of 17.6% at
appreciate any improvement. There were 23% men 1 month, 35.3% at 2 months, and 47.1% at the end of 3
[69]
[71]
and 14% women who noticed improvement in some months . Another study by Nicholas et al. comparing
areas and a few patients, 13% men and 15% women a supplement of green tea extract, omega 3 and 6 fatty
rated that they were worse than before. acids, melatonin, cholecalciferol, betasitosterol, and
soy isoflavones, over a period of 24 weeks (6 months),
DISCUSSION showed 4.9% improvement in terminal hair counts.
Rizer et al. [70] studied the benefit of marine protein
Similar benefit as 68% reduction of hair fall in 1 month supplement to find an overall 8% improvement in
and 85% in 4 months were seen in the present study diameter for villus hair after 6 months. Rizer et al. [70]
was reported by Beer et al. [69] who studied the benefits did not compare terminal hair counts and hair calibre
from a keratin supplement with minerals and vitamins, but suggested that further improvement could be
which showed 12.5% reduction in hair loss over possible if the supplements were continued for 1 year,
Plastic and Aesthetic Research ¦ Volume 4 ¦ September 30, 2017 169