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Rajput                                                                                                                                                                                Cyclical nutritional therapy clinical trial

                 A                                                  A
















                 B                                                  B

















           Figure 5: A: folliscope measurement of hair density before starting   Figure 7: A: temporal receding and thinning in female patient day
           treatment; B: folliscope measurement of hair density after 4 months   one before starting the treatment; B: hair regrowth over temporal
           of nutritional correction and 2% minoxidil         area after 4 months of 2% minoxidil and nutritional treatment

                                                              improvement in density was 10% and the average
                 A                                            calibre improved by 8%. At the end of 1 year follow-
                                                              up, the density had improved 16% and calibre had
                                                              improved 12%. There were 31% patients with no
                                                              change in density or calibre at 6 months. This number
                                                              reduced to 26% non-responders at the end of 1 year
                                                              follow-up in women.

                                                              Villus hair count
                                                              Villus hair counts were recorded initially and compared
                                                              over 2-month intervals for 1 year. The minimum and
                                                              maximum villus hair counts for both the treatment
                                                              groups initially were between 12-35%, these reduced
                 B                                            to between 5-24% at 4 months. The average counts
                                                              again raised to 15-28% at 8 months and remained 10-
                                                              21% at the end of 1 year. Villus hair counts in control
                                                              groups initially were between 14-38% and changed
                                                              marginally at 11-40% at the end of 8 months and were
                                                              between 16-34% at the end of one year.

                                                              Global photography
                                                              The overall rating in the control groups for both men
                                                              and women were similar. The grading in the control
                                                              group which started as no change at 2-4 months,
                                                              improved to a noticeable change in 56% patients by
           Figure 6: A: female pattern frontal hair loss day one before starting   the end of 1 year but none could be rated as good
           the treatment; B: hair regrowth over frontal area after 6 months of 2%
           minoxidil and nutritional correction               improvement. While the rating in the treatment groups
            168                                                                                    Plastic and Aesthetic Research ¦ Volume 4 ¦ September 30, 2017
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