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Chen et al. Neuroimmunol Neuroinflammation 2017;4:46-53 Neuroimmunology and
DOI: 10.20517/2347-8659.2017.04
Neuroinflammation

www.nnjournal.net
Topic: Stroke Open Access

Cerebral ischemia at early postoperative

period of direct revascularization for

moyamoya disease: a case report and

literature review

Xiao-Lin Chen 1, 2* , Li Ma 1, 2, 3* , Yu Chen 1, 2, 3* , Jun-Lin Lu 1, 2, 3 , Xun Ye 1, 2, 3 , Rong Wang 1, 2, 3 , Yuan-Li Zhao 1, 2, 3, 4, 5

1 Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China.
2 China National Clinical Research Center for Neurological Diseases, Beijing 100050, China.
3 Department of Neurosurgery, Peking University International Hospital, Peking University Health Science Center, Beijing 102206, China.
4 Center of Stroke, Beijing Institute for Brain Disorders, Beijing 100050, China.
5 Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing 100050, China.
* Authors contributed equally.
Correspondence to: Dr. Yuan-Li Zhao, Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No. 6 Tiantan Xili,
Dongcheng District, Beijing 100050, China. E-mail: zhaoyuanli@126.com

How to cite this article: Chen XL, Ma L, Chen Y, Lu JL, Ye X, Wang R, Zhao YL. Cerebral ischemia at early postoperative period of direct
revascularization for moyamoya disease: a case report and literature review. Neuroimmunol Neuroinflammation 2017;4:46-53.

Dr. Yuan-Li Zhao is a Professor of Neurosurgery in the Department of Neurosurgery, Beijing Tiantan Hospital,
Capital Medical University and China National Clinical Research Center for Neurological Diseases. He is also
the Neurosurgeon-in-Chief and Chairman of the Department of Neurosurgery, Peking University International
Hospital. He earned his medical degree from Peking Union Medical College in 1996. He was a visiting scholar at
Massachusetts General Hospital, Johns Hopkins Hospital, Mayo Clinic and Barrow Neurological Institute. He is
the Deputy President of the Young Neurosurgeon Committee of Chinese Neurosurgical Society and international
member of American Association of Neurological Surgeons.

ABSTRACT
Article history: Hypoperfusion and hyperperfusion could be causes of early postoperative complications that
Received: 12-01-2017 lead to neurological deterioration in patients with moyamoya diseases (MMD) after superficial
Accepted: 22-02-2017 temporal artery (STA) and middle cerebral artery (MCA) anastomosis. Here, the authors
Published: 24-03-2017 described a case of child-onset bilateral MMD that manifested transient cerebral ischemia
in the contralateral hemisphere after left STA-MCA bypass in young adulthood. A new onset
Key words: of cerebral ischemia in the contralateral hemisphere and transient neurological deterioration
Moyamoya disease, suggested the fragile hemodynamics of MMD during early perioperative period. Serial
cerebral revascularization, evaluation of postoperative cerebral hemodynamics and perfusion might facilitate targeted
transient neurological events, management in patients with unstable or advanced MMD.
perioperative management

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