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Rice et al. Minocycline in spinal cord injury

J.E.A. Larsen, H. Li, P.H. Larsen, R.K. Nuttall microtiter assay for inhibitors. Biochem Pharmacol 1996;52:105-11.
Co-wrote the first draft: T. Rice, J.E.A. Larsen 11. Yong VW, Power C, Forsyth P, Edwards DR. Metalloproteinases
Edited the manuscript: T. Rice, R.K. Nuttall, S. Casha, in biology and pathology of the nervous system. Nat Rev Neurosci
2001;2:502-11.
J. Hurlbert, D.R. Edwards 12. Wells JE, Rice TK, Nuttall RK, Edwards DR, Zekki H, Rivest S, Yong
Co-supervised aspects of the project: S. Casha, J. VW. An adverse role for matrix metalloproteinase 12 after spinal cord
Hurlbert, D.R. Edwards injury in mice. J Neurosci 2003;23:10107-15.
Provided overall supervision of the project and edited 13. Hsu JY, McKeon R, Goussev S, Werb Z, Lee JU, Trivedi A, Noble-
and finalized the manuscript: V.W. Yong Haeusslein LJ. Matrix metalloproteinase-2 facilitates wound healing
events that promote functional recovery after spinal cord injury. J
Neurosci 2006;26:9841-50.
Financial support and sponsorship 14. Noble LJ, Donovan F, Igarashi T, Goussev S, Werb Z. Matrix
This work was supported by an operating grant from metalloproteinases limit functional recovery after spinal cord injury by
the Canadian Institutes of Health Research to VWY modulation of early vascular events. J Neurosci 2002;22:7526-35.
(MOP 133477). 15. Nuttall RK, Pennington CJ, Taplin J, Wheal A, Yong VW, Forsyth PA,
Edwards DR. Elevated membrane-type matrix metalloproteinases in
Conflicts of interest gliomas revealed by profiling proteases and inhibitors in human cancer
The authors have no conflicts of interest to declare. cells. Mol Cancer Res 2003;1:333-45.
16. Larsen PH, Wells JE, Stallcup WB, Opdenakker G, Yong VW. Matrix
Patient consent metalloproteinase-9 facilitates remyelination in part by processing the
inhibitory NG2 proteoglycan. J Neurosci 2003;23:11127-35.
Not applicable. 17. Xue M, Hollenberg MD, Yong VW. Combination of thrombin and
matrix metalloproteinase-9 exacerbates neurotoxicity in cell culture and
Ethics approval intracerebral hemorrhage in mice. J Neurosci 2006;26:10281-91.
All studies involving animals were reviewed and 18. Yong VW. Metalloproteinases: mediators of pathology and regeneration
approved by ethics committee at the University of in the CNS. Nat Rev Neurosci 2005;6:931-44.
Calgary, Canada. 19. Zhao BQ, Wang S, Kim HY, Storrie H, Rosen BR, Mooney DJ, Wang X,
Lo EH. Role of matrix metalloproteinases in delayed cortical responses
after stroke. Nat Med 2006;12:441-5.
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252 Neuroimmunology and Neuroinflammation ¦ Volume 4 ¦ November 28, 2017