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Chen et al. Neuroimmunol Neuroinflammation 2017;4:124-31 Neuroimmunology and
DOI: 10.20517/2347-8659.2017.17
Neuroinflammation

www.nnjournal.net
Original Article Open Access

Analysis of clinical data of viral

encephalitis patients complicated with

epilepsy during the acute phase

Shi-Ying Chen , Wei Ma , Yan-Yan Chen , Xue-Wen Fan 2
1
2
1
1 Department of Neurology, Ningxia Medical University, Yinchuan 750004, Ningxia, China.
2 Department of Neurology, the Cardia-Cerebrovascular Disease Hospital of Ningxia Medical University, Yinchuan 750004, Ningxia, China.
Correspondence to: Prof. Xue-Wen Fan, Department of Neurology, the Cardia-Cerebrovascular Disease Hospital of Ningxia Medical University,
Yinchuan 750004, Ningxia, China. E-mail: nxfxw@163.com
How to cite this article: Chen SY, Ma W, Chen YY, Fan XW. Analysis of clinical data of viral encephalitis patients complicated with epilepsy
during the acute phase. Neuroimmunol Neuroinflammation 2017;4:124-31.
Prof. Xue-Wen Fan is a Chief Physician, Supervisor of Postgraduates, Deputy Head of Current Neurology Branch
of Chinese Medical Association Nerve Infection and Cerebrospinal Fluid Cytology Study Group, Department of
Neurology Branch of Chinese Medical Doctor Association, Vice Chairman of Neuroinfections Disease Specialized
Committee. He specializes in nerve infection and cerebrospinal fluid cytology, cerebrovascular diseases and
dementia study. He published more than 30 papers, edited 4 books, and presided over 2 provincial and ministerial
research projects and 2 scientific research departments.

ABSTRACT

Article history: Aim: To compare the difference between viral encephalitis patients complicated with epilepsy
Received: 29-03-2017 group and those without epilepsy. Methods: The authors retrospectively study 116 cases of
Accepted: 10-05-2017 viral encephalitis patients admitted to the General Hospital of Ningxia Medical University
Published: 11-07-2017 and the Cardia-Cerebrovascular Disease Hospital of Ningxia Medical University from January
2011 to December 2016. There were 39 cases with epilepsy and 77 cases without epilepsy. By
Key words: surveying the Hospital Information System, the authors collected their clinical data including
Viral encephalitis, general situations, medical history, physical examination, clinical presentation, laboratory
epilepsy, examination, cerebrospinal fluid examination, imaging examination, electroencephalogram
treatment, examination (EEG), treatment, and discharge conditions. The authors used SPSS for further
clinical characteristics analysis and statistics. Results: Medical history: there were significant differences between the
two groups in disturbance of consciousness, cognitive dysfunction, and admission conditions
(P < 0.05). No significant differences were found in other clinical manifestations. Auxiliary
examination: in cerebrospinal fluid (CSF) examination, the patients with epilepsy had higher
glucose (P < 0.05). Brain imaging examination shows that cortical involvements in patients
with epilepsy were higher (P < 0.05), and EEG examination showed that patients with
epilepsy were more severe (P < 0.05). No significant differences were found in other auxiliary

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