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could bind cerebellar astrocytes in HE patients but not such as seizures and cognitive dysfunction, as in our
in Hashimoto thyroiditis patients. This may support case. Corticosteroid treatment is successful for HE in
the role of TPOAb in the pathogenesis of Hashimoto’s most cases, however, clinicians should be aware that
encephalopathy. TPOAb is present in 95-100% and TGAb relapses can occur early or even late after tapering of
in 73% of patients with HE. Elevated serum level of steroid use; therefore, a long follow-up period should
TPOAb may be related with vasculitic type Hashimoto’s be recommended.
encephalopathy and elevated serum levels of TPOAb
and TGAb may be with diffuse progressive type of HE. Financial support and sponsorship
However, the elevated titres of these antibodies can This study was supported by the grants from the
be tested in the healthy population. Therefore, the Fujian Province Natural Science Fund (2013J01275,
role of those antibodies and their pathophysiology 2014J01401).
are unknown. In addition, corticosteroid treatment is
successful in most cases, which can further support Conflicts of interest
the diagnosis of HE. Furthermore, other common There are no conflicts of interest.
causes of encephalopathy should be ruled out, such
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