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mitotic figures, necrosis and endothelial proliferation,   Rosenblum M, Mikkelsen T. Can permeability measurements add
           correlated to the subsequent clinico-radiological      to blood volume measurements in differentiating tumefactive
           profile, glioma co-existing with TDL could be reliably   demyelinating lesions from high grade gliomas using perfusion CT?
                                                                  J Neurooncol 2010;97:383‑8.
           excluded. [11]  Our case highlights the importance of   6.   Roemer  SF, Scheithauer  BW,  Varnavas  GG, Lucchinetti  CF.
           meticulous radiopathological inputs required into      Tumefactive demyelination and glioblastoma: a rare collision lesion.
           analysis of butterfly multifocal lesions that is the key   Clin Neuropathol 2011;30:186‑91.
           to guide subsequent management of an evidently     7.   Altintas A, Petek B, Isik N, Terzi M, Bolukbasi F, Tavsanli M, Saip S,
                                                                  Boz C, Aydin T, Arici‑Duz O, Ozer F, Siva A. Clinical and radiological
           treatable condition.                                   characteristics of tumefactive demyelinating lesions: follow‑up study.
                                                                  Mult Scler 2012;18:1448‑53.
           REFERENCES                                         8.   Saini  J, Chatterjee  S, Thomas  B, Kesavadas  C. Conventional
                                                                  and advanced magnetic resonance imaging in tumefactive
                                                                  demyelination. Acta Radiol 2011;52:1159‑68.
           1.   Bourekas EC, Varakis K, Bruns D, Christoforidis GA, Baujan M,   9.   Kepes JJ. Large focal tumor‑like demyelinating lesions of the brain:
              Slone HW, Kehagias D. Lesions of the corpus callosum: MR imaging
              and differential considerations in adults and children. AJR Am J   intermediate entity between multiple sclerosis and acute disseminated
                                                                  encephalomyelitis? A study of 31 patients. Ann Neurol 1993;33:18‑27.
              Roentgenol 2002;179:251‑7.
           2.   Kobayashi M, Shimizu Y, Shibata N, Uchiyama S. Gadolinium   10.  Neelima R, Krishnakumar K, Nair MD, Kesavadas C, Hingwala DR,
              enhancement patterns of tumefactive demyelinating lesions:   Radhakrishnan VV, Nair SS. Tumefactive demyelinating lesions:
                                                                  a clinicopathological correlative study. Indian J Pathol Microbiol
              correlations with  brain biopsy findings and pathophysiology.
              J Neurol 2014;261:1902‑10.                          2012;55:496‑500.
           3.   Lucchinetti CF, Gavrilova RH, Metz I, Parisi JE, Scheithauer BW,   11.  Donev K, Scheithauer BW. Pseudoneoplasms of the nervous system.
                                                                  Arch Pathol Lab Med 2010;134:404‑16.
              Weigand S, Thomsen K, Mandrekar J, Altintas A, Erickson BJ,
              Konig F, Giannini C, Lassmann H, Linbo L, Pittock SJ, Bruck W.
              Clinical and radiographic spectrum of pathologically confirmed
              tumefactive multiple sclerosis. Brain 2008;131:1759‑75.  Cite this article as: Menon R, Thomas B, Easwer HV, Sandhyamani S, Nair A,
           4.   Schwartz KM, Erickson BJ, Lucchinetti C. Pattern of T2 hypointensity   Nair M. A clinically isolated syndrome: butterfly glioma mimic. Neuroimmunol
                                                               Neuroinflammation 2015;2(3):174-8.
              associated with ring‑enhancing brain lesions can help to differentiate
              pathology. Neuroradiology 2006;48:143‑9.         Source of Support: Nil. Conflict of Interest: No.
           5.   Jain R, Ellika S, Lehman NL, Scarpace L, Schultz LR, Rock JP,   Received: 30-10-2014; Accepted: 11-02-2015





















































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