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16. Sargsyan SA, Shearer AJ, Ritchie AM, Burgoon MP, Anderson S,
Hemmer B, Stadelmann C, Gattenlöhner S, Owens GP, Gilden D, Cite this article as: Zhang SC, Liu L, Wang RJ, Tuo HZ, Guo YJ, Yi L,
Bennett JL. Absence of Epstein‑Barr virus in the brain and CSF of Wang DX, Wang JW. Detection of Epstein-Barr virus infection subtype
patients with multiple sclerosis. Neurology 2010;74:1127‑35. in patients with multiple sclerosis by indirect immunofluorescence assay.
17. Jafari N, van Nierop GP, Verjans GM, Osterhaus AD, Middeldorp JM, Neuroimmunol Neuroinflammation 2014;1(1):24-8.
Hintzen RQ. No evidence for intrathecal IgG synthesis to Epstein Barr Source of Support: The work was supported by Beijing Natural Science
virus nuclear antigen‑1 in multiple sclerosis. J Clin Virol 2010;49:26‑31. Foundation (Nos. 7102040, 7132060), National Natural Science Foundation
18. Jaquiéry E, Jilek S, Schluep M, Meylan P, Lysandropoulos A, of China (Nos. 81041020, 81271311 and 81241039), Traditional Chinese
Pantaleo G, Du Pasquier RA. Intrathecal immune responses to EBV Medicine, Beijing Technology Development Fund (No. SF-2007-III-22),
in early MS. Eur J Immunol 2010;40:878‑87. Beijing Excellent Talent Foundation (No. 20071-D0300100062), the
19. Cepok S, Zhou D, Srivastava R, Nessler S, Stei S, Büssow K, high-level technical training project funding of the Beijing health system
Sommer N, Hemmer B. Identification of Epstein‑Barr virus proteins (2011-3-004) and the preferential funding scheme for Beijing city staff to go
abroad. Conflict of Interest: No.
as putative targets of the immune response in multiple sclerosis.
J Clin Invest 2005;115:1352‑60. Received: 04-05-2014; Accepted: 29-05-2014
28 Neuroimmunol Neuroinflammation | Volume 1 | Issue 1 | June 2014