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Page 6 of 13 Tang. Mini-invasive Surg 2020;4:24 I http://dx.doi.org/10.20517/2574-1225.2019.60

Table 3. The position, number and size of myoma uteri of 31 patient (Data of myoma size ≥ 5 cm)
Patient (myoma number) Intramural Subserous Posterior intramural Broad ligament
1 (2) 1 (6) 1 (15)
2 (3) 3 (12, 10, 8)
3 (1) 1 (16)
4 (1) 1 (14)
5 (1) 1 (14)
6 (1) 1 (9)
7 (2) 2 (14, 6)
8 (2) 1 (6) 1 (10)
9 (2) 2 (12, 8)
10 (1) 1 (10)
11 (2) 2 (10, 6)
12 (1) 1 (16)
13 (1) 1 (8)
14 (5) 3 (8, 6, 5) 2 (10, 8)
15 (1) 1 (12)
16 (1) 1 (8)
17 (2) 2 (8, 7)
18 (2) 2 (8, 6)
19 (1) 1(10)
20 (1) 1 (10)
21 (2) 2 (20, 5)
22 (1) 1 (8)
23 (1) 1 (12)
24 (1) 2 (10)
25 (1) 1 (15)
26 (1) 1 (15)
27 (2) 2 (13, 5)
28 (3) 2 (8, 7) 1 (5)
29 (2) 1 (6.5) 1 (5.5)
30 (2) 1 (5) 1 (9)
31 (2) 2 (10, 5)
Total (average) 36 (9.26 ± 3.46 cm) 6 (10.67 ± 4.18 cm) 5 (9.30 ± 4.49 cm) 4 (3.74 ± 1.87 cm)

accounted for 70%, subserous myoma dropped to 12%, posterior intramural myoma accounted for 10%,
and broad ligament myoma accounted for 8% [Figure 1D].

As shown in Figure 2, we analyzed the relationship between the number of myomas and the blood loss,
showing no significant relationship. We also calculated the relationship between the maximum diameter of
myoma in a patient with the blood loss, showing a significant relationship.

We calculated the relationships between operation time and the number and maximum diameter of
myomas. As shown in Figure 3A, there was no significant relationship between operation time and the
number of myomas removed. The operation time became longer as the maximum diameter of myoma
increased, but this relationship did not reach significance [Figure 3B].

As to the learning curve, we used the CUSUM method to calculate the learning curve by operation time
[Figure 4]. No learning curve was noted in our study.

Concerning to perioperative complications, there were three cases (9.7%) with blood loss over 500 mL, but
all could be corrected after intraoperative blood transfusion without any sequalae. There were three cases
(9.7%) with postoperative fever > 38 °C and persisted over 48 h. However, all subsided and the patients were
discharged after three days of intravenous antibiotics. All 31 patients completed their surgery by single-port
laparoscope without changing to multiport laparoscopy or laparotomy. There were no major complications
such as bowel, ureter, bladder injuries, or incisional hernia.