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Ornaghi et al. Mini-invasive Surg 2021;5:42 https://dx.doi.org/10.20517/2574-1225.2021.50 Page 5 of 17

LN yield was higher for RARC compared with
ORC, with a median of 27 nodes (IQR 7-57)
compared with 20.5 nodes (IQR 0-57) (P <
0.001). The overall rate of N+ disease was low
between both groups (P = 0.89)
The overall complication rate was 75.4%, with
no difference in rates between groups (76.3%
vs. 73.9%, respectively, P = 0.83)
The majority of complications (89.5% vs.
82.3%) were < 3 CCS complications
Overall 30- and 90-day readmission rates were
24% and 29.8%, respectively, with no difference
observed between ORC or RARC groups (P =
0.67 and P = 0.68)
[17]
Whittum et al. , Retrospective 118 RARC Median of 9 IC (106); others Age, BMI, ASA score, - Surgical: OT, type of UD, 17 patients (14%) showed a gynecological organ
2018 (monocentric months (IQR (12) NAC, prior EBL, ICU, LOS, 30- and 90- invasion at pathological specimen. These
study) 6-13) for abdominal/pelvic day complications, 30- and patients had more LVI at TURBT (82% vs. 46%,
organ surgery, prior RT, LVI 90-day readmission; P = 0.006), trigonal tumours at TURBT (59% vs.
invasion; 23 at TURBT, tumor site - Pathological: pT stage 18%, P = 0.001), multifocal disease (65% vs.
months (IQR at TURBT, histology at (gynecological organ 33%, P = 0.01), (71% vs. 22%, P < 0.001), PSMs
8-45) for no TURBT invasion), pN stage, (24% vs. 4%; P = 0.02), and they less commonly
organ histology, PSMs; demonstrated pure urothelial carcinoma at
invasion - Oncological: AC; 30- and TURBT (18% vs. 66%, P < 0.001)
90-day OS There was no statistically significant difference
between the two groups in terms of hospital or
ICU stay, complications, readmissions, mortality
at 30 and 90 days
On multivariate analysis, significant predictors of
gynecological organ invasion were pN positive
disease (OR 6.48, 95%CI: 1.64-25.51, P =
0.008), trigonal tumour location (OR 5.72, 95%
CI: 1.39-23.61, P = 0.02), and presence of variant
histology (OR 18.52, 95%CI: 3.32-103.4, P =
0.001)
[22]
Tyritzis et al. , Retrospective 70 (62 male, 8 RARC (nerve Median of iN Age, sex, BMI, ASA - Surgical: OT, type of They recorded negative margins in 69 of 70
2013 (monocentric female) sparing-RARC in 30.3 months score, preoperative PLND, nerve sparing, EBL, patients (98.6%). Clavien 3-5 complications
study) all female) (IQR 12.7- TNM, preoperative LOS, ≥ 30-day/90-day occurred in 22/70 patients (31.4%) at 30-day
35.6) grade, concomitant complications according to and 13/70 (18.6%) at > 30-day. At 90-day, the
CIS, NAC. CCS; overall complication rate was 58.5%. Clavien < 3
- Pathological: pT stage, and Clavien ≥ 3 complications were recorded in
pN stage, concomitant CIS, 15/70 patients (21.4%) and 26/70 (37.1%),
PSMs, GS, LN yield; respectively
- Oncological: 24-month Kaplan-Meier estimates for RFS, CSS and OS at
recurrence, recurrence 24 months were 80.7%, 88.9%, and 88.9%,
location, RFS, CCS, OS; respectively
- Functional: 6/12-month Daytime and nighttime continence at 12 months
daytime and nighttime reaches 80%-90% in men and 70% women. At
continence (≤ 1 pad/die), 12 months, 46 men (74.2%) and 2 of 3 evaluable
6/12-month potency and females (66.7%) were continent. One female