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Page 10 of 23                                                                              George et al. Mini-invasive Surg 2024;8:4  https://dx.doi.org/10.20517/2574-1225.2023.102


                              Table 3. Table of AI applications in capsule endoscopy for vascular lesions and angiodysplasias

                                                            Year of        Study        Study                                                                                 AI
                              Ref.      Application                                                Aim and goals                             Training/Validation dataset              Results
                                                            publication    design       location                                                                              type
                              Gan       Vascular lesions and   2008        Retrospective China     Develop computer-aided screening and      Dataset of 236 patients with lesion,   IPS  Median sensitivity of 74.2%
                                  [44]
                              et al.    angiodysplasias                                            diagnosis for enteric lesions in CE       and 86 without lesion for training and
                                                                                                                                             validation
                              Leenhardt  Vascular lesions and   2018       Retrospective France    Utilise CNN for detection of AGD in SB-CE   Training: 300 normal frames,   CNN     Sensitivity of 100%, specificity
                                  [54]
                              et al.    angiodysplasias                                            images                                    300 AGD frames                           of 96%
                                                                                                                                             Testing: 300 normal frames,
                                                                                                                                             300 AGD frames

                              Arieira   Vascular lesions and   2019        Retrospective Portugal  Evaluate accuracy and efficacy of “TOP 100”   Testing: 97 patients         TOP     No sensitivity or specificity.
                                  [45]
                              et al.    angiodysplasias                                            feature                                                                    100     Accuracy of 83.5% for P2
                                                                                                                                                                                      lesions,
                                                                                                                                                                                      95.5% for AGD, 56.7% for
                                                                                                                                                                                      ulcers,
                                                                                                                                                                                      100% for active bleeding sites
                              Vieira    Vascular lesions and   2019        Retrospective Portugal  Automatic detection of AGD in WCE videos  Dataset: 27 images from KID      MLP     MLP: sensitivity of 96.60%,
                                  [46]                                                                                                              [110]
                              et al.    angiodysplasias                                                                                      database  ,                      and     specificity of 94.08%
                                                                                                                                             additional 248 AGD images,       SVM     SVM: sensitivity of 96.58%,
                                                                                                                                             550 normal images                        specificity of 92.24%
                              Vezakis   Vascular lesions and   2019        Retrospective Greece    Combining of low-level image analysis, feature  Training: 350 normal images,   CNN  Sensitivity of 92.7%, specificity
                                  [47]
                              et al.    angiodysplasias                                            detection, and machine learning for AGD   196 bubble images,                       of 99.5%
                                                                                                   detection in WCE images                   75 blood vessel images,
                                                                                                                                             104 AGD images
                                                                                                                                             Testing: 3 full-length WCE
                              Leenhardt  Vascular lesions and   2019       Retrospective France    Develop CNN methodology to detect GIA in   Training: 300 normal frames,    CNN     Sensitivity of 100%, specificity
                                  [48]
                              et al.    angiodysplasias                                            SB-CE                                     300 GIA frames GIA                       of 96%
                                                                                                                                             Testing: 300 normal frames,
                                                                                                                                             300 GIA frames
                              Tsuboi    Vascular lesions and   2020        Retrospective Japan     Development of CNN system based on SSMB   Training: 2,237 angiodysplasia images  CNN  Sensitivity of 98.8%, specificity
                                  [49]
                              et al.    angiodysplasias                                            for small bowel AGD detection             Testing: 488 AGD images,                 of 98.4%
                                                                                                                                             10,000 normal images
                              Aoki      Vascular lesions and   2021        Retrospective Japan     Construct CNN based system for various    Training: 44,684 images of       CNN     No sensitivity or specificity
                                  [50]
                              et al.    angiodysplasias                                            abnormality detection                     abnormalities and 21,344 normal          reported. Accuracy of 100% for
                                                                                                                                             images                                   mucosal breaks,
                                                                                                                                             Testing: 379 full small-bowel CE         97% for AGD, 99% for
                                                                                                                                             videos                                   protruding lesions,
                                                                                                                                                                                      and 100% for blood content
                              Hwang     Vascular lesions and   2021        Retrospective Korea     Develop CNN algorithm for categorisation of   Training: 11,776 haemorrhagic lesions,  CNN  Sensitivity of 97.61%,
                                  [51]
                              et al.    angiodysplasias                                            SBCE videos into haemorrhagic lesions and   18,448 ulcerative lesions,             specificity of 96.04%
                                                                                                   ulcerative lesions                        30,224 normal images
                                                                                                                                             Testing: 5,760 images
                              Hosoe     Vascular lesions and   2022        Retrospective Japan     Detect common findings on SBCE images using  Training: 33 SBCE cases       CNN     Sensitivity of 93.4%, specificity
                                  [52]
                              et al.    angiodysplasias                                            CNN framework with aim to reduce false-   Testing: 35 SBCE cases                   of 97.8%
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