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 Table 4. Table of AI applications in capsule endoscopy for polyps and tumours

 Year of   Study
 Ref.  Application  Study design  Aim and goals  Training/Validation dataset  AI type Results
 publication  location
 [55]
 Li et al.  Polyps and   2011  Retrospective  China  Utilise textural feature based   Training: 450 normal samples,   KNN   Best Results:
 tumours  on multi-scale local binary   450 tumour samples     MLP      sensitivity of 92.33%,
 pattern for tumour detection  Testing: 150 normal samples,    SVM      specificity of 88.67%
                    150 tumour samples
 Karargyris and   Polyps and   2011  Retrospective  America  Utilising log Gabor filters for   Polyps testing: 10 frames with polyps,   SVM  Ulcer detection:
 [56]
 Bourbakis  tumours  feature extraction to detect   40 normal frames    sensitivity of 75.0%,
 polyps and ulcers  Ulcer testing: 20 ulcer frames,                     specificity of 73.3%
                    30 non-ulcer frames                                 Polyp detection:
                                                                        sensitivity of 100%,
                                                                        specificity of 67.5%
 Barbosa   Polyps and   2012  Retrospective  Portugal  Extracting textural features to   Dataset for training and testing: 700 tumour   MLP  Sensitivity of 93.9%,
 [57]
 et al.  tumours  detect polyps and tumours  images, 2,300 normal images  specificity of 93.1%
 Mamonov   Polyps and   2014  Retrospective  USA/Portugal Development of binary   Dataset for training and testing:   BC  Per frame: sensitivity
 [58]
 et al.  tumours  classifier for tumour detection  230 tumour images, 18,738 normal images  of 47.4%, specificity
 geometrical analysis and                                               of 90.2%
 texture content                                                        Per polyp: sensitivity
                                                                        of 81.25%, specificity
                                                                        of 93.47%
 [59]
 Liu et al.  Polyps and   2016  Retrospective  China  Integrating multi-scale curvelet  Training: WCE videos of 15 patients   SVM  Sensitivity of 97.8%,
 tumours  and fractal technology into   Testing: 900 normal frames,     specificity of 96.7%
 textural features for polyp   900 tumour frames
 detection
 Yuan and   Polyps and   2017  Retrospective  China  Construction of SSAEIM for   Testing: 1,000 bubble images, 1,000 TIs, 1,000   SSAEIM Polyps: sensitivity of
 [62]
 Meng  tumours  polyp detection  CIs, 1,000 polyp images                98%, specificity of
                                                                        99%
                                                                        Bubbles: sensitivity of
                                                                        99.5%, specificity of
                                                                        99.17%
                                                                        TIs: sensitivity of
                                                                        99%,
                                                                        specificity of 100%
                                                                        CIs: sensitivity of
                                                                        95.5%,
                                                                        specificity of 99.17%
 Blanes-Vidal   Polyps and   2019  Retrospective  Denmark  Developed algorithm to match  Training: 39,550 images   CNN  Sensitivity of 97.1%,
 [74]
 et al.  tumours  CCE and colonoscopy polyps   Testing: 8,476 images    specificity of 93.3%
 and construct CNN for polyp
 detection
 [63]
 Saito et al.  Polyps and   2020  Retrospective  Japan  Constructing CNN model for   Training: 30,584 protruding lesion images   CNN  Sensitivity of 90.7%,
 tumours  protruding lesion detection  Testing: 7,507 protruding lesion images, 10,000   specificity of 79.8%
                    normal images
 [60]
 Yang et al.  Polyps and   2020  Retrospective  China  Development of algorithm   Testing: 500 normal, 500 polyp images  SVM  Sensitivity of 95.80%,
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